Results 211 to 220 of about 53,329 (292)
5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng +14 more
wiley +1 more source
Effects of intravenous phosphodiesterase inhibitors and corticosteroids on severe meconium aspiration syndrome. [PDF]
Shao JI, Lin CH, Yang YH, Jeng MJ.
europepmc +1 more source
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Caffeine and Headache: Exploring the Multifaceted Relationship
ABSTRACT Purpose To explore the multifaceted relationship between caffeine and headache disorders, focusing on its dual role as both an analgesic and a potential trigger and to summarize the mechanisms underlying its anti‐nociceptive effects. Method This narrative review synthesizes evidence from experimental, clinical, and epidemiological studies on ...
Mona Hussein +6 more
wiley +1 more source
ABSTRACT Double‐stranded DNA coming from, for example, viruses, bacteria, or apoptotic cells is recognized by the cGAS‐STING signaling pathway comprising the cyclic GMP‐AMP synthase (cGAS) and the stimulator of interferon genes (STING) receptors. The pathway induces type I interferon response and activates transcription of interferon‐stimulated genes ...
András Harazin +9 more
wiley +1 more source
ABSTRACT Background Chronic thromboembolic pulmonary disease (CTEPD) leads to chronic total occlusions (CTOs) of the pulmonary arteries in a minority of patients. Treatment of CTOs with balloon pulmonary angioplasty (BPA) may substantially improve patient hemodynamics but presents unique technical challenges and has previously been associated with a ...
Elliot J. Stein +4 more
wiley +1 more source
Taking Advantage of the Selectivity of Histone Deacetylases and Phosphodiesterase Inhibitors to Design Better Therapeutic Strategies to Treat Alzheimer's Disease. [PDF]
Cuadrado-Tejedor M +9 more
europepmc +1 more source
ABSTRACT Cerebral vasospasm is a major complication of aneurysmal subarachnoid hemorrhage and a key contributor to delayed cerebral ischemia, which remains a leading cause of morbidity despite standard therapy with nimodipine and induced hypertension.
Paul Cardozo Gil +7 more
wiley +1 more source
Potential synergistic effect of phosphodiesterase inhibitors with chemotherapy in lung cancer. [PDF]
Domvri K +7 more
europepmc +1 more source
ABSTRACT Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, potentially curable form of pulmonary hypertension, with limited data in pregnancy. We describe a 37‐year‐old woman with progressive dyspnea, back pain, and cough, whose evaluation revealed severe right ventricular enlargement, high pulmonary pressures, and extensive V/Q ...
Hassan Ahangar +3 more
wiley +1 more source

