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The role of phosphodiesterase inhibitors in impotence
Expert Opinion on Investigational Drugs, 1997Penile erection is mediated by nitric oxide (NO) and its second messenger cyclic guanosine monophosphate (cGMP). The activity of cGMP is modulated by the enzyme phosphodiesterase (PDE). The most important physiological isoform of the enzyme in the penis is PDE5.
openaire +2 more sources
Advancements in Phosphodiesterase 5 Inhibitors: Unveiling Present and Future Perspectives
Pharmaceuticals, 2023Ahmed Elhady +2 more
exaly
Phosphodiesterase Type 5 Inhibitors for Premature Ejaculation: A Systematic Review and Meta-analysis
European Urology Focus, 2017Marrissa Martyn-St James +2 more
exaly

