Results 191 to 200 of about 84,264 (300)

In Salmonella Typhimurium, YiiD Modulates cAMP Levels in Lag Phase During Growth on Succinate

open access: yesMolecular Microbiology, EarlyView.
The YiiD enzyme, found by others to perform a redundant role in fatty acid biosynthesis, is found to be unexpectedly required for the early increase in cAMP in lag phase during growth on succinate. This intriguing finding suggests a mechanistic link may exist between fatty acid biosynthesis and catabolite repression. ABSTRACT In Salmonella Typhimurium (
John A. Ciemniecki   +2 more
wiley   +1 more source

Long‐Term Safety and Efficacy of Once‐Daily and Proactive Twice‐Weekly Roflumilast Cream 0.05% for Mild‐to‐Moderate Atopic Dermatitis in Children Aged 2–5 Years From a 52‐Week, Phase 3 Trial (INTEGUMENT‐OLE)

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Background INTEGUMENT‐PED/NCT04845620, a 4‐week, phase 3 trial, demonstrated efficacy and safety of roflumilast cream 0.05% in children aged 2–5 years with mild‐to‐moderate atopic dermatitis (AD). A phase 3 open‐label extension trial (INTEGUMENT‐OLE [NCT04804605]) investigated long‐term outcomes continuing roflumilast cream for ≤ 56 weeks ...
Lawrence F. Eichenfield   +14 more
wiley   +1 more source

Beyond traditional pharmacology: evaluating phosphodiesterase inhibitors in autism spectrum disorder. [PDF]

open access: yesNeuropsychopharmacology
Padovan-Neto FE   +3 more
europepmc   +1 more source

Phosphodiesterase inhibitors as adjunctive therapies for tuberculosis

open access: yesEBioMedicine, 2016
Bintou Ahmadou Ahidjo, William R. Bishai
doaj   +1 more source

Identification of potent and orally efficacious phosphodiesterase inhibitors in Cryptosporidium parvum-infected immunocompromised male mice. [PDF]

open access: yesNat Commun
Ajiboye J   +12 more
europepmc   +1 more source

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