Results 271 to 280 of about 87,967 (330)

Late airway obstruction and neutrophil infiltration in sensitized mice after antigen provocation were suppressed by selective and non-selective phosphodiesterase inhibitors

open access: gold, 1997
Osamu Kaminuma   +8 more
openalex   +1 more source

Vitamin D deficiency induces erectile dysfunction: Role of superoxide and Slpi

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 15, Page 3669-3687, August 2025.
Background and Purpose Epidemiological studies suggest a relationship between vitamin D deficiency and erectile dysfunction (ED). We hypothesized that vitamin D deficiency or vitamin D receptor (VDR) knockout causes ED and analysed the underlying molecular mechanisms.
Miguel A. Olivencia   +14 more
wiley   +1 more source

Prostacyclin Therapy as Adjunctive Treatment for Pulmonary Hypertension in Pediatric Heart Transplantation: A Case Report

open access: yesPediatric Transplantation, Volume 29, Issue 5, August 2025.
ABSTRACT Background Elevated pulmonary vascular resistance is a significant risk factor for right‐ventricle failure and poor outcomes following pediatric heart transplantation. Pulmonary vasodilator therapy can help manage symptoms and improve heart transplant candidacy.
Anusha Konduri   +7 more
wiley   +1 more source

Vasopressin‐Sensitive Aqp2 Regulation Mediated by the TAZ‐NR4A1 Axis in Renal Collecting Duct Cells

open access: yesThe FASEB Journal, Volume 39, Issue 13, 15 July 2025.
The TAZ‐NR4A1 axis was identified as a critical regulator of vasopressin‐induced AQP2 expression, essential for water homeostasis. Conditional TAZ‐knockout mice showed polyuria and a significant decrease in AQP2 expression in collecting ducts. In mpkCCDc11 cells, TAZ knockdown significantly impaired vasopressin‐mediated AQP2 expression independently of
Hong Seok Choi   +6 more
wiley   +1 more source

Phosphodiesterase inhibitors as therapeutics for traumatic brain injury. [PDF]

open access: yesCurr Pharm Des, 2015
Titus DJ   +3 more
europepmc   +1 more source

Antiplatelet and cardiovascular effects of NM-702, a novel multiple inhibitor of cyclic-nudeotide phosphodiesterases and thromboxane A synthase.

open access: gold, 1996
Nohutomo Tsuruzoe   +6 more
openalex   +1 more source

Pregnancy Outcomes of Targeted Synthetic Disease‐Modifying Antirheumatic Drugs Among Patients With Autoimmune Diseases: A Scoping Review

open access: yesArthritis Care &Research, Volume 77, Issue 7, Page 916-927, July 2025.
Objective Targeted synthetic disease‐modifying antirheumatic drugs (tsDMARDs) have expanded the management of autoimmune diseases, including rheumatic diseases. As the use of these drugs grows, it is important to understand their effects on pregnancy.
Vienna Cheng   +7 more
wiley   +1 more source

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