Results 61 to 70 of about 2,803,213 (206)
International Journal of General Medicine, 2014 Bader Alsaikhan, Khalid Alrabeeah, Serge CarrierMcGill University Health Centre, Montreal, Quebec, QC, CanadaAbstract: Lower urinary tract symptoms (LUTS) and erectile dysfunction increase with age.
Alsaikhan B, Alrabeeah K, Carrier S
doaj
Chemical principles of instability and self-organization in reacting and diffusive systems [PDF]
arXiv, 2022 How patterns and structures undergo symmetry breaking and self-organize within biological systems from initially homogeneous states is a key issue for biological development. The activator-inhibitor (AI) mechanism, derived from reaction-diffusion (RD) models, has been widely believed to be the elementary mechanism for biological pattern formation. This
arxiv
The effect of phosphodiesterase-5 inhibitors on cerebral blood flow in humans: A systematic review
Journal of Cerebral Blood Flow and Metabolism, 2017 Agents that augment cerebral blood flow (CBF) could be potential treatments for vascular cognitive impairment. Phosphodiesterase-5 inhibitors are vasodilating drugs established in the treatment of erectile dysfunction (ED) and pulmonary hypertension.
M. Pauls +6 more
semanticscholar +1 more source
Phosphodiesterase-5 inhibitors: Raynaud's and beyond
Indian Journal of Rheumatology, 2017 Phosphodiesterases (PDE) are a group of ubiquitously present enzymes involved in regulation of various cellular pathways. PDE5 acts to metabolize cyclic guanosine monophosphate (GMP).
Sanat Phatak +3 more
doaj
The role of phosphodiesterase inhibitors in the management of pulmonary vascular diseases
Global Cardiology Science & Practice, 2014 Phosphodiesterase inhibitors (PDE) can be used as therapeutic agents for various diseases such as dementia, depression, schizophrenia and erectile dysfunction in men, as well as congestive heart failure, chronic obstructive pulmonary disease, rheumatoid ...
G. Butrous
semanticscholar +1 more source
Prediction of 5-hydroxytryptamine Transporter Inhibitor based on Machine Learning [PDF]
arXiv, 2019 In patients with depression, the use of 5-HT reuptake inhibitors can improve the condition. Topological fingerprints, ECFP4, and molecular descriptors were used. Some SERT and small molecules combined prediction models were established by using 5 machine learning methods. We selected the higher accuracy models(RF, SVM, LR) in five-fold cross-validation
arxiv
Expert Opinion on Therapeutic Patents, 2014 Introduction: PDEs are key enzymes in the adenosine and guanosine cyclic nucleotides (cAMP and cGMP) signaling cascade. Their inhibition increases cyclic nucleotide levels inside the cell.
Ana MartÃnez, C. Gil
semanticscholar +1 more source
Sexual function in hypertensive patients receiving treatment
Vascular Health and Risk Management, 2006 Thorsten Reffelmann, Robert A KlonerUniversity of Southern California, The Heart Institute, Good Samaritan Hospital, Division of Cardiovascular Medicine, Keck School of Medicine, Los Angeles, CA, USAAbstract: In many forms of erectile dysfunction (ED ...
Thorsten Reffelmann, Robert A Kloner
doaj
Anti-inflammatory effects of theophylline and selective phosphodiesterase inhibitors
Allergology International, 1996 Theophylline has been used in the treatment of airway diseases, for more than 50 years with benefit thought to be derived from its ability to elicit bronchodilatation.
Katharine H. Banner, Clive P. Page
doaj +1 more source
Freeze the BCI until the user is ready: a pilot study of a BCI inhibitor [PDF]
arXiv, 2011 In this paper we introduce the concept of Brain-Computer Interface (BCI) inhibitor, which is meant to standby the BCI until the user is ready, in order to improve the overall performance and usability of the system. BCI inhibitor can be defined as a system that monitors user's state and inhibits BCI interaction until specific requirements (e.g.
arxiv