Results 81 to 90 of about 2,803,213 (206)

A framework for generalized group testing with inhibitors and its potential application in neuroscience [PDF]

arXiv, 2018
The main goal of group testing with inhibitors (GTI) is to efficiently identify a small number of defective items and inhibitor items in a large set of items. A test on a subset of items is positive if the subset satisfies some specific properties. Inhibitor items cancel the effects of defective items, which often make the outcome of a test containing ...
arxiv  

The use of antimuscarinics, phosphodiesterase type V inhibitors and phytotherapy for lower urinary tract symptoms in men

Asian Journal of Urology, 2017
Besides the mainstay of α-blockers and 5α-reductase inhibitors, other forms of medical therapy complete the armamentarium in the treatment of lower urinary tract symptoms (LUTS) in men.
Kok Kit Ng, Foo Cheong Ng
doaj  

Successful Shortening of Tuberculosis Treatment Using Adjuvant Host-Directed Therapy with FDA-Approved Phosphodiesterase Inhibitors in the Mouse Model

PLoS ONE, 2012
Global control of tuberculosis (TB), an infectious disease that claims nearly 2 million lives annually, is hindered by the long duration of chemotherapy required for curative treatment.
M. Maiga, Nisheeth Agarwal, Nicole C. Ammerman, Radhika Gupta, Haidan Guo, Marama C. Maiga, S. Lun, W. Bishai   +7 more
semanticscholar   +1 more source

Use of Phosphodiesterase Inhibitors in the Postoperative Period of Skin Flaps: A Systematic Review. [PDF]

Plast Reconstr Surg Glob Open, 2023
Daronch OT, Marcante RFR, Neto AAP, Viterbo F.   +3 more
europepmc   +1 more source

Design of a folding inhibitor of the HIV-1 Protease [PDF]

arXiv, 2004
Being HIV-1-PR an essential enzyme in the viral life cycle, its inhibition can control AIDS. Because the folding of single domain proteins, like HIV-1-PR is controlled by local elementary structures (LES, folding units stabilized by strongly interacting, highly conserved amino acids) which have evolved over myriads of generations to recognize and ...
arxiv  

The Effects of Cyclic Nucleotide Phosphodiesterase Inhibitors on Ejaculated Porcine Spermatozoan Metabolism1 [PDF]

, 1973
David L. Garbers, Neal L. First, Sharon K. Gorman, Henry A. Lardy   +3 more
openalex   +1 more source

Recent developments of phosphodiesterase inhibitors: Clinical trials, emerging indications and novel molecules. [PDF]

Front Pharmacol, 2022
Bondarev AD, Attwood MM, Jonsson J, Chubarev VN, Tarasov VV, Liu W, Schiöth HB.   +6 more
europepmc   +1 more source

A short review on structure and role of cyclic-3',5'-adenosine monophosphate-specific phosphodiesterase 4 as a treatment tool

Journal of Research in Pharmacy Practice, 2015
Cyclic nucleotide phosphodiesterases (PDEs) are known as a super-family of enzymes which catalyze the metabolism of the intracellular cyclic nucleotides, cyclic-3',5'-adenosine monophosphate (cAMP), and cyclic-3',5'-guanosine monophosphate that are ...
Nahid Eskandari, Omid Mirmosayyeb, Gazaleh Bordbari, Reza Bastan, Zahra Yousefi, Alireza Andalib   +5 more
doaj   +1 more source

Small Universal Petri Nets with Inhibitor Arcs [PDF]

arXiv, 2013
We investigate the problem of construction of small-size universal Petri nets with inhibitor arcs. We consider four descriptional complexity parameters: the number of places, transitions, inhibitor arcs, and the maximal degree of a transition, each of which we try to minimize.
arxiv  

Binding of inhibitor alters kinetic and physical properties of extracellular cyclic AMP phosphodiesterase from Dictyostelium discoideum. [PDF]

, 1979
Richard H. Kessin, Seth J. Orlow, Reneé Shapiro, Jakob Franke   +3 more
openalex   +1 more source