Results 201 to 210 of about 45,588 (281)

CD8+ Tissue‐Resident Memory T Cells in Health and Disease

MedComm, Volume 7, Issue 7, July 2026.
CD8+ TRM cells are at the center of immunity, mediating potent local innate and adaptive immune responses. While TRM cells mediate protective immunity against infections and tumors, they also contribute to pathological inflammation in autoimmune conditions.
Yu‐Han Ai, Ting‐Ting Xu, Sen Lin, Meng‐Yu Xiao, Yun‐Xia Lin, Hao‐Wen Ma, Yue‐Yang Liu, Yao‐Jie Wang, Lu‐Ning Yin, Mei Huang, Yong‐Da Liu, Chao Zhu, Xiao‐Ting Zhu, Ji‐Hang Yuan   +13 more
wiley   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Emerging Medications in Facial Nerve Recovery: A Systematic Review and Meta‐Analysis

OTO Open, Volume 10, Issue 3, July-September 2026.
Abstract Objective To systematically review the literature for medical therapies that promote facial nerve regeneration and recovery. Data Sources PubMed/Medline, Embase, and SCOPUS databases were searched for English‐language studies published from inception through May 2025.
Kimberly Chan, Cheng Ma, Bao Y. Sciscent, Andreacarola Urso, Neerav Goyal, Jessyka G. Lighthall   +5 more
wiley   +1 more source

Fecal Proteomics Suggest Potential Biomarkers for Non‐Alcoholic Fatty Liver Disease and Steatohepatitis

PROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni, Luisa Pieroni, Noemi Fiaschini, Francesca Palone, Mariateresa Mancuso, Roberta Vitali   +5 more
wiley   +1 more source

Crataegus oxyacantha Extract Enhances Cardiac Adaptation and Reduces Oxidative‐Inflammatory Stress in Broiler Chickens Raised at High Altitude Under Cold Stress

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Crataegus oxyacantha extract at 0.4 mL/L improved cardiac function in broilers under cold stress and high altitude by increasing nitric oxide synthase gene expression, boosting nitric oxide, reducing endothelin‐1 gene expression, and lowering oxidative‐inflammatory stress, offering a natural solution to mitigate pulmonary hypertension syndrome ...
Behnam Ahmadipour, Hossein Hassanpour, Samira Abaszadeh, Majid Kalantar   +3 more
wiley   +1 more source

Comparing bridging drug therapy approaches prior to balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension: a prospective analysis from the national UK CURATE registry. [PDF]

Open Heart
Li OM, Ghani H, Appenzeller P, Amaral-Almeida L, Bambrough P, Cannon JE, Taboada D, Bunclark KL, Toshner M, Sheares K, Coghlan JG, Pepke-Zaba J, Hoole SP.   +12 more
europepmc   +1 more source

Low testosterone levels in men at age 31 associates with future risk of prediabetes and type 2 diabetes: A birth cohort study

Andrology, Volume 14, Issue 5, Page 1209-1219, July 2026.
Abstract Objective We aimed to investigate the association of a low serum testosterone concentration with the risk of abnormal glucose metabolism (i.e., prediabetes and type 2 diabetes) in men at a 15‐year follow‐up. Study population and methods In a population birth cohort, men with low testosterone (testosterone < 12.1 nmol/L, n = 136) and normal ...
Tuomisto A, Pinola P, Pesonen P, Franks S, Martikainen H, Tapanainen JS, Niinimäki M, Morin‐Papunen L   +7 more
wiley   +1 more source

Regulation of cAMP levels in osteocytes by mechano-sensitive focal adhesion kinase and phosphodiesterase 8A. [PDF]

iScience
Papaioannou G, Sato T, Houghton C, Yan C, Kotsalidis PE, Strauss KE, Dean T, Mazur CM, Nelson AJ, Stokes MP, Gardella TJ, Wein MN.   +11 more
europepmc   +1 more source

Affinity Proteomics‐Based Non‐Invasive Detection of Clinically Significant Liver Disease

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 1, Page 74-88, July 2026.
Using UK Biobank proteomic data, we identified a five‐protein score reflecting hepatic stellate cell activation and hepatocellular injury that predicts major adverse liver outcomes and clinically significant fibrosis, with consistent performance validated in two independent cohorts (patients with HIV and alpha1‐antitrypsin deficiency).
Sriram Balasubramani, Katharina Remih, Anna Sophie Karl, Julia Alexandra Borchert, Christina Schrader, Malin Fromme, Can Kayatekin, Bailin Zhang, Mikhail Levit, Pavithra Krishnaswami, Louise E. van Eekeren, Leo A. B. Joosten, Twan Otten, Petra Tomanová, Pavel Strnad   +14 more
wiley   +1 more source