Results 181 to 190 of about 45,588 (281)

T-1032, a novel specific phosphodiesterase type 5 inhibitor, increases venous compliance in anesthetized rats [PDF]

, 2001
Tsunehisa Noto, Tomihiro Ikeo, Koji Yano, Kohei Kikkawa, Hirotaka Inoue   +4 more
core   +1 more source

Ejaculatory Dysfunction and Minimally Invasive Surgical Treatments (MIST) for Male Lower Urinary Tract Symptoms Secondary to Benign Prostatic Enlargement

Trends in Urology &Men's Health, Volume 17, Issue 4, August 2026.
ABSTRACT While transurethral resection of the prostate (TURP) is considered the standard surgical treatment in symptomatic benign prostatic enlargement (BPE) secondary to benign prostatic hyperplasia (BPH), it is not without surgical morbidities and has adverse impact on various sexual function domains such as ejaculatory dysfunction (EjD) and erectile
Haijun Yao, Tao Wang, Shan‐Chao Zhao, Lei Zheng, Rui Jiang, Han Wu, Jingjing Gao, Baibing Yang, Yuzhuo Yang, Haocheng Lin, Eric Chung   +10 more
wiley   +1 more source

Acute effect of phosphodiesterase type 5 inhibitor tadalafil on plasma redox status in healthy men [PDF]

, 2017
Luigi Di Luigi, Roberta Ceci, Guglielmo Duranti, Paolo Sgrò, Stefania Sabatini   +4 more
core   +1 more source

Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?

Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley   +1 more source

Polarized effects of adenosine on blood–brain barrier integrity: Tightening from the luminal and opening from the abluminal side

British Journal of Pharmacology, Volume 183, Issue 16, Page 4761-4777, August 2026.
Background and Purpose Adenosine as a signalling molecule modifies blood–brain barrier (BBB) tightness in pathological conditions. Our aim was to investigate the direct and polarized effects of adenosine on the BBB using co‐culture and in vivo models. Experimental Approach The expression of adenosine receptors was measured by qRT‐PCR.
András Harazin, Gabriela Hurtado‐Alvarado, Lilla Barna, Arturo Contis‐Montes de Oca, Rocío Ruíz‐Manzano, Krisztián Laczi, András Kincses, Gergő Porkoláb, Gang Chen, Beatriz Gómez‐González, Mária A. Deli   +10 more
wiley   +1 more source

The Role of Water in Protein–Ligand Binding: Decisive Factor, Annoying Feature, or Indispensable Control Element: In Any Case, a Major Challenge

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Water influences ligand binding to a protein. Replacing, picking up, or modulating water dynamics restructures the water arrangement and affects the enthalpic and entropic signatures of binding. Whether the two properties add up or cancel each other out determines the expected ligand affinity enhancement.
Gerhard Klebe
wiley   +1 more source

Analysis of short-term treatment with the phosphodiesterase type 5 inhibitor tadalafil on long bone development in young rats.

Am J Physiol Endocrinol Metab, 2018
Wang L, Jia H, Tower RJ, Levine MA, Qin L.   +4 more
europepmc   +1 more source

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, Volume 13, Issue 38, 9 July 2026.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

Prevention of nitroglycerin tolerance in vitro by T0156, a selective phosphodiesterase type 5 inhibitor [PDF]

, 2008
Chi Wai Lau, Vivian Wing Yan Lee, Yu Huang, Fung Ping Leung, Limin Lu, Cui Qing Liu, Xiaoqiang Yao   +6 more
core   +1 more source