Results 51 to 60 of about 28,180 (258)

Aspects of the Control of Phosphoenolpyruvate Carboxykinase Gene Transcription [PDF]

Journal of Biological Chemistry, 2009
Abstract This article reviews our current understanding of factors that regulate transcription of the gene for PEPCK-C, focusing on the effect of methylation on gene expression. It also provides insight into the evolutionary status of the PEPCK-C gene.
Lea Reshef, Gabriela Aleman, Richard W. Hanson, Jianqi Yang, Hanoch Cassuto   +4 more
openaire   +3 more sources

Combined transcriptomic-(1)H NMR metabonomic study reveals yhat monoethylhexyl phthalate stimulates adipogenesis and glyceroneogenesis in human adipocytes [PDF]

, 2011
Adipose tissue is a major storage site for lipophilic environmental contaminants. The environmental metabolic disruptor hypothesis postulates that some pollutants can promote obesity or metabolic disorders by activating nuclear receptors involved in the ...
Beale E. G., Beale E. G., Becker K., Beckonert O., Berman T., Cadoudal T., Cadoudal T., Chakravarty K., Chantal Benelli, Christianson J. L., Chui P. C., Claude Forest, Claus S. P., Cloarec O., Desvergne B., Durmaz E., Ellero S. L., Eriksson L., Eubank D. W., Feige J. N., Feige J. N., Franck Letourneur, Franckhauser S., Fukuwatari T., Gregoire F. M., Grun F., Grun F., Guan H. P., Hanson R. W., Hanson R. W., Hatch E. E., Huang da W., Huber W. W., Hurst C. H., Isabelle de Waziers, Martinelli M. I., Millward C. A., Mullerova D., Nicolas Cagnard, Okuno A., Philippe H. Beaune, Rink J. D., Roberts L. D., Roberts R. A., Sandrine Ellero-Simatos, Sandrine P. Claus, Sears D. D., Si Y., Stahlhut R. W., Su X., Targett-Adams P., Tordjman J., Trygg J., Tusher V. G., van Harmelen V., Veselkov K. A., Weuve J., Yoo H., Zancanaro C., Zhang Y. H.   +59 more
core   +2 more sources

Hypoglycemic mechanisms of Polygonatum sibiricum polysaccharide in db/db mice via regulation of glycolysis/gluconeogenesis pathway and alteration of gut microbiota

Heliyon, 2023
Polygonatum rhizoma polysaccharide (PP) is a main ingredient of Polygonatum rhizoma, which is both food and traditional herbal medicine. In this study, we aimed to investigate the hypoglycemic effect of PP and the underlying mechanisms in db/db mice. Our
Xuan Chen, Ye-ling Tong, Ze-ming Ren, Si-si Chen, Xi-yu Mei, Qing-yun Zhou, Guan-hai Dai   +6 more
doaj   +1 more source

Elucidating fish oil-induced milk fat depression in dairy sheep: Milk somatic cell transcriptome analysis [PDF]

, 2017
9 páginas, 4 figuras.In this study, RNA sequencing was used to obtain a comprehensive profile of the transcriptomic changes occurring in the mammary gland of lactating sheep suffering from fish oil-induced milk fat depression (FO-MFD).
Arranz, Juan José, Frutos, Pilar, Gutiérrez Gil, Beatriz, Hervás, Gonzalo, Suárez-Vega, Aroa, Toral, Pablo G.   +5 more
core   +1 more source

Optimum flux rerouting for efficient production of naringenin from acetate in engineered Escherichia coli

Biotechnology for Biofuels and Bioproducts, 2022
Background Microbial production of naringenin has received much attention owing to its pharmaceutical applicability and potential as a key molecular scaffold for various flavonoids.
Dong Hwan Kim, Hyun Gyu Hwang, Gyoo Yeol Jung   +2 more
doaj   +1 more source

LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]

, 2014
The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart, Brewer, Heather M, Camp, David G, II, Depuydt, Geert, Petyuk, Vladislav A, Smith, Richard D, Smolders, Arne, Xie, Fang   +7 more
core   +2 more sources

Nitrogen recycling from the xylem in rice leaves: dependence upon metabolism and associated changes in xylem hydraulics [PDF]

, 2016
Measurements of amino acids in the guttation fluid and in the xylem exudates of cut leaves from intact plants provide evidence of the remarkable efficiency with which these nitrogenous compounds are reabsorbed from the xylem sap. This could be achieved
Engelsberger, Ewers, Gaspar, Gerrard Wheeler, Hacke, Hayakawa, Jomain-Baum, Karen J. Bailey, Leegood, Mae, Nolte, Richard C. Leegood, Sakurai, Walker, Walker   +14 more
core   +1 more source

Overexpression of PCK1 Gene Antagonizes Hepatocellular Carcinoma Through the Activation of Gluconeogenesis and Suppression of Glycolysis Pathways

Cellular Physiology and Biochemistry, 2018
Background/Aims: Gluconeogenesis, a reverse process of glycolysis, is suppressed in neoplastic livers. Cytoplasmic phosphoenolpyruvate carboxykinase (PEPCK-C/PCK1, encoded by PCK1) is a step limiting enzyme of gluconeogenesis.
Yufu Tang, Yibing Zhang, Chunhui Wang, Zhongyi Sun, Longfei Li, Shuqun Cheng, Wenping Zhou   +6 more
doaj   +1 more source

Untersuchungen zur Rolle der Phosphoenolpyruvat-Carboxykinase und des NADP+-Malat-Enzyms in der filamentösen Phaeophycee Ectocarpus siliculosus [PDF]

, 2003
In der filamentösen Braunalge Ectocarpus siliculosus liegen die Enzyme Phosphoenolpyruvat-Carboxykinase (PEPCK) und das NADP+-Malat-Enzym in hohen Aktivitäten vor. Die Beteiligung beider Enzyme an einem für die Alge vorgeschlagenen C4/CAM-
Busch, Sylvia, Galland, Paul (Prof. Dr.)
core   +1 more source

sRNA scr5239 Involved in Feedback Loop Regulation of Streptomyces coelicolor Central Metabolism

Frontiers in Microbiology, 2020
In contrast to transcriptional regulation, post-transcriptional regulation and the role of small non-coding RNAs (sRNAs) in streptomycetes are not well studied. Here, we focus on the highly conserved sRNA scr5239 in Streptomyces coelicolor.
Franziska Engel, Elena Ossipova, Per-Johan Jakobsson, Michael-Paul Vockenhuber, Beatrix Suess   +4 more
doaj   +1 more source