Association of PCK1 with Body Mass Index and Other Metabolic Features in Patients With Psychotropic Treatments. [PDF]
Weight gain is a major health problem among psychiatric populations. It implicates several receptors and hormones involved in energy balance and metabolism.
Aubry, J.M. +15 more
core +2 more sources
LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]
The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart +7 more
core +2 more sources
Background Microbial production of naringenin has received much attention owing to its pharmaceutical applicability and potential as a key molecular scaffold for various flavonoids.
Dong Hwan Kim +2 more
doaj +1 more source
Polygonatum rhizoma polysaccharide (PP) is a main ingredient of Polygonatum rhizoma, which is both food and traditional herbal medicine. In this study, we aimed to investigate the hypoglycemic effect of PP and the underlying mechanisms in db/db mice. Our
Xuan Chen +6 more
doaj +1 more source
Untersuchungen zur Rolle der Phosphoenolpyruvat-Carboxykinase und des NADP+-Malat-Enzyms in der filamentösen Phaeophycee Ectocarpus siliculosus [PDF]
In der filamentösen Braunalge Ectocarpus siliculosus liegen die Enzyme Phosphoenolpyruvat-Carboxykinase (PEPCK) und das NADP+-Malat-Enzym in hohen Aktivitäten vor. Die Beteiligung beider Enzyme an einem für die Alge vorgeschlagenen C4/CAM-
Busch, Sylvia, Galland, Paul (Prof. Dr.)
core +1 more source
Background/Aims: Gluconeogenesis, a reverse process of glycolysis, is suppressed in neoplastic livers. Cytoplasmic phosphoenolpyruvate carboxykinase (PEPCK-C/PCK1, encoded by PCK1) is a step limiting enzyme of gluconeogenesis.
Yufu Tang +6 more
doaj +1 more source
Stanniocalcin 1 effects on the renal gluconeogenesis pathway in rat and fish [PDF]
The mammalian kidney contributes significantly to glucose homeostasis through gluconeogenesis. Considering that stanniocalcin 1 (STC1) regulates ATP production, is synthesized and acts in different cell types of the nephron, the present study ...
Abu Hossain +80 more
core +1 more source
Comprehensive Detection of Genes Causing a Phenotype using Phenotype Sequencing and Pathway Analysis [PDF]
Discovering all the genetic causes of a phenotype is an important goal in functional genomics. In this paper we combine an experimental design for multiple independent detections of the genetic causes of a phenotype, with a high-throughput sequencing ...
Gronenberg, Luisa +3 more
core +11 more sources
Phosphoenolpyruvate Carboxykinase Assayed at Physiological Concentrations of Metal Ions Has a High Affinity for CO2 [PDF]
The effect of Mn2+/Mg2+ concentration on the activity of intact, homogeneous phosphoenolpyruvate carboxykinase (PEPCK) from leaves of the C4 grass, Guinea grass (Panicum maximum), have been investigated.
Acheson, R.M. +3 more
core +1 more source
Repression of glucocorticoid-stimulated angiopoietin-like 4 gene transcription by insulin. [PDF]
Angiopoietin-like 4 (Angptl4) is a glucocorticoid receptor (GR) primary target gene in hepatocytes and adipocytes. It encodes a secreted protein that inhibits extracellular LPL and promotes adipocyte lipolysis.
Chen, Tzu-Chieh +6 more
core +1 more source

