Results 61 to 70 of about 29,231 (198)

Aryl Hydrocarbon Receptor Activation by Dioxin Targets Phosphoenolpyruvate Carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-inducible Poly(ADP-ribose) Polymerase (TiPARP)*

Journal of Biological Chemistry, 2013
Background: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-activated aryl hydrocarbon receptor (AHR) decreases gluconeogenesis by suppressing phosphoenolpyruvate carboxykinase (PEPCK) transcription via TCDD-inducible poly(ADP-ribose)-polymerase (TiPARP ...
Silvia Diani-Moore, S. Zhang, P. Ram, A. Rifkind   +3 more
semanticscholar   +1 more source

FAHD1 and mitochondrial metabolism: a decade of pioneering discoveries

The FEBS Journal, EarlyView.
This paper reviews a decade of research on FAHD1, an important yet underappreciated enzyme in mitochondrial metabolism. FAHD1 plays a crucial role in energy production, oxidative stress regulation, and processes related to aging and overall health.
Elia Cappuccio, Max Holzknecht, Michèle Petit, Anne Heberle, Yana Rytchenko, Athanasios Seretis, Ciro L. Pierri, Hubert Gstach, Pidder Jansen‐Dürr, Alexander K. H. Weiss   +9 more
wiley   +1 more source

Effects of maternal nutrient restriction, intrauterine growth restriction, and glucocorticoid exposure on phosphoenolpyruvate carboxykinase‐1 expression in fetal baboon hepatocytes in vitro

Journal of medical primatology, 2013
The objective of this study was to develop a cell culture system for fetal baboon hepatocytes and to test the hypotheses that (i) expression of the gluconeogenic enzyme phosphoenolpyruvate carboxykinase‐1 (PEPCK‐1) is upregulated in hepatocytes isolated ...
Cun Li, Zhenju Shu, Shuko Lee, Madhulika B. Gupta, T. Jansson, P. Nathanielsz, A. Kamat   +6 more
semanticscholar   +1 more source

Guard cell‐specific glycine decarboxylase manipulation affects Arabidopsis photosynthesis, growth and stomatal behavior

New Phytologist, EarlyView.
Summary Photorespiration is a mandatory metabolic repair shunt of carbon fixation by the Calvin–Benson cycle in oxygenic phototrophs. Its extent depends mainly on the CO2 : O2 ratio in chloroplasts, which is regulated via stomatal movements. Despite a comprehensive understanding of the role of photorespiration in mesophyll cells, its role in guard ...
Hu Sun, Nils Schmidt, Tracy Lawson, Martin Hagemann, Stefan Timm   +4 more
wiley   +1 more source

Fructose-1,6-bisphosphatase, Malate Dehydrogenase, Isocitrate Lyase, Phosphoenolpyruvate Carboxykinase, Glyceraldehyde-3-phosphate Dehydrogenase, and Cyclophilin A are secreted in Saccharomyces cerevisiae grown in low glucose

Communicative & Integrative Biology, 2013
Our previous studies demonstrated that the key gluconeogenic enzyme fructose-1,6-bisphosphatase is secreted when Saccharomyces cerevisiae are starved of glucose for a prolonged period of time.
Bennett J. Giardina, H. Chiang
semanticscholar   +1 more source

Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets. [PDF]

PLoS ONE, 2014
In this study, gestational sows were fed control or betaine-supplemented diets (3 g/kg) throughout the pregnancy, and the newborn piglets were used to elucidate whether maternal dietary betaine affected offspring hepatic gluconeogenic genes through ...
Demin Cai, Yimin Jia, Haogang Song, Shiyan Sui, Jingyu Lu, Zheng Jiang, Ruqian Zhao   +6 more
doaj   +1 more source

Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components

Modern Agriculture, Volume 3, Issue 1, June 2025.
The regulatory network system of mTOR regulates lactose, milk fat, and milk protein. Milk is urgently needed for the strong development of the dairy industry to meet the growing demand and ensure that the nutritional needs of the world's population are met.
RongNuo Li, YiNing Zheng, HuiJun Geng, Lu Deng   +3 more
wiley   +1 more source

Inflammation inhibits the expression of phosphoenolpyruvate carboxykinase in liver and adipose tissue

Innate Immunity, 2012
Inhibition of adipocyte triglyceride biosynthesis is required for fatty acid mobilization during inflammation. Triglyceride biosynthesis requires glycerol 3-phosphate and phosphoenolpyruvate carboxykinase (PEPCK) plays a key role. We demonstrate that LPS,
K. Feingold, A. Moser, J. Shigenaga, C. Grunfeld   +3 more
semanticscholar   +1 more source

A Synthetic Facultative CAM‐Like Shuttle in C3 Rice Plants

Advanced Science, Volume 12, Issue 13, April 3, 2025.
This study utilizes gene editing and multigene stacking to design a facultative CAM‐like metabolic pathway that includes a stomatal regulation module, a carboxylation module, a decarboxylation module, and a malate transport module. A facultative CAM‐like metabolic pathway is created in C₃ rice, achieving compatibility between the C₃ cycle and the CAM ...
Suting Wu, Kaining Jin, Haoshu Li, Guoxin Chen, Liying Zhang, Jinwen Yang, Shanshan Zhai, Yanni Li, Xuehui Sun, Xuean Cui, Jing Sun, Tiegang Lu, Zhiguo Zhang   +12 more
wiley   +1 more source

Computational and Pharmacological Evaluation of Carveol for Antidiabetic Potential

Frontiers in Pharmacology, 2020
BackgroundCarveol is a natural drug product present in the essential oils of orange peel, dill, and caraway seeds. The seed oil of Carum Carvi has been reported to be antioxidant, anti-inflammatory, anti-hyperlipidemic, antidiabetic, and hepatoprotective.
Muhammad Shabir Ahmed, Arif-ullah Khan, Lina Tariq Al Kury, Fawad Ali Shah   +3 more
doaj   +1 more source