Results 1 to 10 of about 10,651 (216)

Phosphoglucomutase comes into the spotlight

Journal of Experimental Botany, 2023
This article comments on:Ortega-Martínez P, Roldán M, Díaz-Troya S, Florencio FJ. 2023. Stress response requires an efficient glycogen and central carbon metabolism connection by phosphoglucomutases in cyanobacteria.
Sofia Doello, Karl Forchhammer
exaly   +3 more sources

Phosphoglucomutase 5 suppresses gallbladder cancer progression by inhibiting lactate-driven STAT3 signaling [PDF]

Translational Oncology
Gallbladder cancer (GBC) is a highly aggressive malignancy of the biliary tract with limited therapeutic options. Phosphoglucomutase 5 (PGM5), a key enzyme in glucose metabolism, has been implicated as a tumor suppressor in several cancers, yet its role ...
Wencong Ma, Cheng Zhang, Anjiang Gou, Mingtai Hu, Yao Huang, Xiaoqing Jiang, Jianyang Ao, Jinghan Wang   +7 more
doaj   +2 more sources

Phosphoglucomutase Is Not the Target for Galactose Toxicity in Plants

Frontiers in Plant Science, 2020
Plants synthesize a number of different oligomeric or polymeric sugars containing galactose. During growth and development some of these carbohydrates are metabolized or remodeled releasing galactose as a breakdown product.
Christian G Huber, Raimund Tenhaken, Roland Reischl   +2 more
exaly   +3 more sources

Phosphoglucomutase A-mediated metabolic adaptation is essential for antibiotic and disease persistence in Mycobacterium tuberculosis [PDF]

mSystems
The long-term survival of Mycobacterium tuberculosis (Mtb) requires efficient use of host resources and uninterrupted access to host-derived nutrients.
Taruna Sharma, Shaifali Tyagi, Rahul Pal, Jayendrajyoti Kundu, Sonu Kumar Gupta, Vishawjeet Barik, Vaibhav Kumar Nain, Manitosh Pandey, Prabhanjan Dwivedi, Bhishma Narayan Panda, Yashwant Kumar, Ranjan Kumar Nanda, Samrat Chatterjee, Amit Kumar Pandey   +13 more
doaj   +2 more sources

Association between phosphoglucomutase-1 gene y420h polymorphism and type 2 diabetes mellitus: A Case-control study

Archives of Medicine and Health Sciences, 2021
Background and Aim: Phosphoglucomutase 1 (PGM1) is an enzyme that catalyzes the key step that links glycogen synthesis with glucose metabolism. Single nucleotide polymorphism (SNP) (rs11208257) is a functional variant in the PGM1 gene that codes for this
K S Praveen Kumar, Prabhakar Kamarthy, Sharath Balakrishna, M S Manu, Sureshkumar Ramaswamy   +4 more
doaj   +1 more source

S-Assimilation Influences in Carrageenan Biosynthesis Genes during Ethylene-Induced Carposporogenesis in Red Seaweed Grateloupia imbricata

Marine Drugs, 2022
The synthesis of cell-wall sulfated galactans proceeds through UDP galactose, a major nucleotide sugar in red seaweed, whilst sulfate is transported through S-transporters into algae.
Diana del Rosario-Santana, Rafael R. Robaina, Pilar Garcia-Jimenez   +2 more
doaj   +1 more source

Modified Monosaccharides Content of Xanthan Gum Impairs Citrus Canker Disease by Affecting the Epiphytic Lifestyle of Xanthomonas citri subsp. citri

Microorganisms, 2021
Xanthomonas citri subsp. citri (X. citri) is a plant pathogenic bacterium causing citrus canker disease. The xanA gene encodes a phosphoglucomutase/phosphomannomutase protein that is a key enzyme required for the synthesis of lipopolysaccharides and ...
Simone Cristina Picchi, Laís Moreira Granato, Maria Júlia Festa Franzini, Maxuel Oliveira Andrade, Marco Aurélio Takita, Marcos Antonio Machado, Alessandra Alves de Souza   +6 more
doaj   +1 more source

Jasmonates disrupt carrageenan synthesis during carposporogenesis in the red seaweed Grateloupia imbricata

Frontiers in Marine Science, 2023
In this study, we monitored changes in cell wall sulfated galactans in the red seaweed Grateloupia imbricata after the rapid (48 h) induction of cystocarp maturation and carpospore development by the volatile hormone methyl jasmonate (MEJA). Synthesis of
Diana Del Rosario-Santana, Rafael Robaina, Pilar Garcia-Jimenez   +2 more
doaj   +1 more source

Glucose-1,6-Bisphosphate, a Key Metabolic Regulator, Is Synthesized by a Distinct Family of α-Phosphohexomutases Widely Distributed in Prokaryotes

mBio, 2022
The reactions of α-d-phosphohexomutases (αPHM) are ubiquitous, key to primary metabolism, and essential for several processes in all domains of life. The functionality of these enzymes relies on an initial phosphorylation step which requires the presence
Niels Neumann, Simon Friz, Karl Forchhammer   +2 more
doaj   +1 more source

The Glaesserella parasuis phosphoglucomutase is partially required for lipooligosaccharide synthesis

Veterinary Research, 2020
Lipooligosaccharides (LOSs) are virulence determinants of Glaesserella parasuis, a pathogen of the respiratory tract of pigs. We previously reported that disruption of the galU or galE gene in G. parasuis results in increased sensitivity to porcine serum,
Saixiang Feng, Aihua Chen, Xiaobing Wang, Zhichao Pan, Siqi Xu, Huiwen Yu, Bin Zhang, Ming Liao   +7 more
doaj   +1 more source