Results 11 to 20 of about 10,651 (216)

Metabolic modulation: Pneumocystis phosphoglucomutase is a target influencing host recognition

The Cell Surface
Herein, this manuscript explores the significance of the phosphoglucomutase (PGM) enzyme in Pneumocystis spp., focusing on its role in fungal surface mannoprotein formation.
Theodore J. Kottom, Eva M. Carmona, Bernd Lepenies, Andrew H. Limper   +3 more
doaj   +2 more sources

Multiple phenotypes in phosphoglucomutase 1 deficiency [PDF]

, 2014
BACKGROUND Congenital disorders of glycosylation are genetic syndromes that result in impaired glycoprotein production. We evaluated patients who had a novel recessive disorder of glycosylation, with a range of clinical manifestations that included ...
et al, Tegtmeyer, Laura C
core   +2 more sources

The inhibition of phosphoglucomutase by beryllium [PDF]

Biochemical Journal, 1966
1. The inhibition of phosphoglucomutase by beryllium has been examined. 2. Inhibition by beryllium does not occur unless a complex-forming agent such as cysteine or imidazole is present. It is therefore similar to activation by magnesium. 3. The inhibition is progressive and the rate follows first-order kinetics, which may be defined by a bimolecular ...
W N, Aldridge, M, Thomas
openaire   +2 more sources

Candidate pathogenicity factor/effector proteins of ‘Candidatus Phytoplasma solani’ modulate plant carbohydrate metabolism, accelerate the ascorbate–glutathione cycle, and induce autophagosomes

Frontiers in Plant Science, 2023
The pathogenicity of intracellular plant pathogenic bacteria is associated with the action of pathogenicity factors/effectors, but their physiological roles for most phytoplasma species, including ‘Candidiatus Phytoplasma solani’ are unknown.
Marina Dermastia, Špela Tomaž, Špela Tomaž, Rebeka Strah, Rebeka Strah, Tjaša Lukan, Anna Coll, Barbara Dušak, Barbara Dušak, Barbara Anžič, Timotej Čepin, Stefanie Wienkoop, Aleš Kladnik, Maja Zagorščak, Monika Riedle-Bauer, Christina Schönhuber, Wolfram Weckwerth, Wolfram Weckwerth, Kristina Gruden, Thomas Roitsch, Maruša Pompe Novak, Maruša Pompe Novak, Günter Brader   +22 more
doaj   +1 more source

Sensitivity of yeast to lithium chloride connects the activity of YTA6 and YPR096C to translation of structured mRNAs.

PLoS ONE, 2020
Lithium Chloride (LiCl) toxicity, mode of action and cellular responses have been the subject of active investigations over the past decades. In yeast, LiCl treatment is reported to reduce the activity and alters the expression of PGM2, a gene that ...
Maryam Hajikarimlou, Houman Moteshareie, Katayoun Omidi, Mohsen Hooshyar, Sarah Shaikho, Tom Kazmirchuk, Daniel Burnside, Sarah Takallou, Narges Zare, Sasi Kumar Jagadeesan, Nathalie Puchacz, Mohan Babu, Myron Smith, Martin Holcik, Bahram Samanfar, Ashkan Golshani, Ashkan Golshani   +16 more
doaj   +1 more source

Stoichiometric Conversion of Maltose for Biomanufacturing by In Vitro Synthetic Enzymatic Biosystems

BioDesign Research, 2022
Maltose is a natural α-(1,4)-linked disaccharide with wide applications in food industries and microbial fermentation. However, maltose has scarcely been used for in vitro biosynthesis, possibly because its phosphorylation by maltose phosphorylase (MP ...
Guowei Li, Xinlei Wei, Ranran Wu, Wei Zhou, Yunjie Li, Zhiguang Zhu, Chun You   +6 more
doaj   +1 more source

Two Phosphoglucomutase Paralogs Facilitate Ionophore-Triggered Secretion of the Toxoplasma Micronemes

mSphere, 2017
Paralogs of the widely prevalent phosphoglucomutase (PGM) protein called parafusin function in calcium (Ca2+)-mediated exocytosis across eukaryotes. In Toxoplasma gondii, the parafusin-related protein 1 (PRP1) has been associated with Ca2+-dependent ...
Sudeshna Saha, Bradley I. Coleman, Rashmi Dubey, Ira J. Blader, Marc-Jan Gubbels   +4 more
doaj   +1 more source

Allomorphy as a mechanism of post-translational control of enzyme activity

Nature Communications, 2020
β-phosphoglucomutase (βPGM) from Lactococcus lactis is a phosphoryl transfer enzyme required for catabolism of trehalose and maltose. Coupled analyses of multiple βPGM structures and enzymatic activity lead to the proposal of allomorphy — a post ...
Henry P. Wood, F. Aaron Cruz-Navarrete, Nicola J. Baxter, Clare R. Trevitt, Angus J. Robertson, Samuel R. Dix, Andrea M. Hounslow, Matthew J. Cliff, Jonathan P. Waltho   +8 more
doaj   +1 more source

Inactivation of the phosphoglucomutase gene pgm in Corynebacterium glutamicum affects cell shape and glycogen metabolism

Bioscience Reports, 2013
In Corynebacterium glutamicum formation of glc-1-P (α-glucose-1-phosphate) from glc-6-P (glucose-6-phosphate) by α-Pgm (phosphoglucomutase) is supposed to be crucial for synthesis of glycogen and the cell wall precursors trehalose and ...
Bernhard J. Eikmanns, Gerd M. Seibold   +1 more
doaj   +1 more source

miR-1293 acts as a tumor promotor in lung adenocarcinoma via targeting phosphoglucomutase 5 [PDF]

PeerJ, 2021
Background Lung adenocarcinoma (LUAD) is the most common histologic subtype of lung cancer. Studies have found that miR-1293 is related to the survival of LUAD patients. Unfortunately, its role in LUAD remains not fully clarified.
Bing Chen, Shiya Zheng, Feng Jiang
doaj   +2 more sources