CT295 Is Chlamydia trachomatis’ Phosphoglucomutase and a Type 3 Secretion Substrate
The obligate intracellular bacteria Chlamydia trachomatis store glycogen in the lumen of the vacuoles in which they grow. Glycogen catabolism generates glucose-1-phosphate (Glc1P), while the bacteria can take up only glucose-6-phosphate (Glc6P).
Sébastien Triboulet +7 more
doaj +1 more source
PGM1 suppresses colorectal cancer cell migration and invasion by regulating the PI3K/AKT pathway
Background Phosphoglucomutase 1 (PGM1) is known for its involvement in cancer pathogenesis. However, its biological role in colorectal cancer (CRC) has remained unknown. Here, we studied the functions and mechanisms of PGM1 in CRC.
Zhewen Zheng +5 more
doaj +1 more source
The mechanism of the phosphoglucomutase reaction. Studies on rabbit muscle phosphoglucomutase with flux techniques [PDF]
1. The kinetics of phosphoglucomutases from different sources are discussed and it is concluded that on the available evidence there are in all cases three possible mechanisms for the reaction. These are an indirect transfer of phosphate involving the phosphoenzyme (mechanism 1), a direct transfer of phosphate (mechanism 2), and an intermolecular ...
H G, Britton, J B, Clarke
openaire +2 more sources
SUBTYPE DETERMINATION OF PHOSPHOGLUCOMUTASE (PGM) AND GROUP- SPECIFIC COMPONENT (Gc) BY ISOELECTRIC FOCUSING AMONG SOME IRANIAN POPULATIONS [PDF]
A total of 781 serum and 827 red cell samples from four populations of Iran (Kashan, Ardestan, Asrara and Ardabil) were sub-typed by isoelectric focusing for group-specific componet and red cell enzyme Phosphoglucomutase, locus one, respectively ...
S.Y. Seyedna
doaj +1 more source
Limitations of galactose therapy in phosphoglucomutase 1 deficiency
Introduction: Phosphoglucomutase 1 deficiency (PGM1 deficiency) has been identified as both, glycogenosis and congenital disorder of glycosylation (CDG).
Kristine Nolting +15 more
doaj +1 more source
Inter- and intra-population genetic variability of introduced silkworm (Bombyx mori L.) strains raised in Bulgaria [PDF]
The genetic variability of four populations belonging to two introduced silkworm strains (Bombyx mori L.) of various origins has been studied using isoenzymic analysis of six enzyme systems. Nonspecific esterases, phosphoglucomutase, malate dehydrogenase,
Teodora Staykova
doaj
Hyper IgE syndrome‐related disease treated with dupilumab: A case report
Phosphoglucomutase 3 (PGM3) catalyzes the glycosylation of immune system precursor proteins. Its impairment leads to severe infections and other developmental, musculoskeletal, and nervous system defects. We present a case of a 2‐month‐old female patient
Andrew S. Kao +3 more
doaj +1 more source
ABSTRACT Dunaliella species are among the most significant biological sources of carotenoids, notably beta‐carotene. Given that chemical synthesis offers a more cost‐effective alternative to biotechnological cultivation, optimizing production strategies is essential for economic viability.
Camylle Guimarães Scheliga +3 more
wiley +1 more source
Isoenzyme-based approach was applied to compare Trichinella spiralis, T. britovi and T. pseudospiralis species. Among 13 enzyme systems examined, esterase (EST), malic enzyme (ME) and phosphoglucomutase (PGM) have been found as fully diagnostic, with no ...
Šnábel V. +3 more
doaj +1 more source
Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source

