Results 11 to 20 of about 31,695 (232)

Phosphoglycerate kinase polymorphism in Drosophila [PDF]

open access: yesBiochemical Genetics, 1973
Uploaded by Plazi for TaxoDros. We do not have abstracts.
G K, Chew, D W, Cooper
core   +8 more sources

An in vivo metabolic approach for deciphering the product specificity of glycerate kinase proves that both E. coli's glycerate kinases generate 2-phosphoglycerate. [PDF]

open access: yesPLoS ONE, 2015
Apart from addressing humanity's growing demand for fuels, pharmaceuticals, plastics and other value added chemicals, metabolic engineering of microbes can serve as a powerful tool to address questions concerning the characteristics of cellular ...
Lior Zelcbuch   +7 more
doaj   +3 more sources

Myopathy and parkinsonism in phosphoglycerate kinase deficiency

open access: yesMuscle and Nerve, 2010
AbstractA 25‐year‐old man with exertional myoglobinuria had no evidence of hemolytic anemia, but he had severe parkinsonism that was responsive to levodopa. Phosphoglycerate kinase (PGK) activity was markedly decreased in muscle, and molecular analysis of thePGK1gene identified the p.T378P mutation that was recently reported in a patient with isolated ...
Paul Greene, Michio Hirano
exaly   +4 more sources

Targeting phosphoglycerate kinases by tatridin A, a natural sesquiterpenoid endowed with anti-cancer activity, using a proteomic platform

open access: yesFrontiers in Molecular Biosciences, 2023
Tatridin A (TatA) is a germacrane sesquiterpenoid containing one E-double bond and one Z-double bond in its 10-membered ring, which is fused to a 3-methylene-dihydrofuran-2-one moiety.
Giusy Ferraro   +8 more
doaj   +1 more source

Blockade of PGK1 and ALDOA enhances bilirubin control of Th17 cells in Crohn’s disease

open access: yesCommunications Biology, 2022
Unconjugated bilirubin modulates Th17-cell metabolism in Crohn’s disease by limiting glycolysis and through downregulation of phosphoglycerate-kinase-1 (PGK1) and aldolase-A (ALDOA).
Marta Vuerich   +13 more
doaj   +1 more source

Standard Gibbs Energy of Metabolic Reactions: III The 3‑Phosphoglycerate Kinase Reaction [PDF]

open access: yesACS Omega, 2018
Anton Wangler   +3 more
doaj   +2 more sources

A model for stimulation of enzyme activity by a competitive inhibitor based on the interaction of terazosin and phosphoglycerate kinase 1 [PDF]

open access: yesProceedings of the National Academy of Sciences of the United States of America
Eric B Taylor   +2 more
exaly   +2 more sources

Phosphoglycerate Mutase Cooperates with Chk1 Kinase to Regulate Glycolysis

open access: yesiScience, 2020
Summary: Dysregulated glycolysis, including the cancerous Warburg effect, is closely involved in pathological mechanisms of diseased states. Among glycolytic enzymes, phosphoglycerate mutase (PGAM) has been known to exert certain physiological impact in ...
Takumi Mikawa   +10 more
doaj   +1 more source

Comparing the folding and misfolding energy landscapes of phosphoglycerate kinase. [PDF]

open access: yes, 2011
Partitioning of polypeptides between protein folding and amyloid formation is of outstanding pathophysiological importance. Using yeast phosphoglycerate kinase as model, here we identify the features of the energy landscape that decide the fate of the ...
Gottfried Köhler   +8 more
core   +1 more source

Predatory Strategies of Myxococcus xanthus: Prey Susceptibility to OMVs and Moonlighting Enzymes

open access: yesMicroorganisms, 2023
Predatory outer membrane vesicles (OMVs) secreted by myxobacteria fuse readily with the outer membranes of Gram-negative bacteria, introducing toxic cargo into their prey.
Allison S. Zwarycz   +4 more
doaj   +1 more source

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