Results 271 to 280 of about 219,778 (281)

Discovery of 4-morpholino-pyrimidin-6-one and 4-morpholino-pyrimidin-2-one-containing Phosphoinositide 3-kinase (PI3K) p110β isoform inhibitors through structure-based fragment optimisation

Bioorganic and Medicinal Chemistry Letters, 2012
Fabrizio Giordanetto
exaly  

Editorial [Hot Topic: Phosphoinositide 3-Kinase Pathway Inhibitors: Pharmacology, Metabolism & Drug Development (Guest Editor: Marco Falasca)]

Current Medicinal Chemistry, 2011
Marco Falasca
exaly  

AKT/PKB and Other D3 Phosphoinositide-Regulated Kinases: Kinase Activation by Phosphoinositide-Dependent Phosphorylation

Annual Review of Biochemistry, 1999
Tung O Chan, S E Rittenhouse, Philip N Tsichlis   +2 more
exaly  

Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma.

Journal of Medicinal Chemistry, 2006
V. Pomel, Jasna Klicic, David Covini, Dennis Church, J. Shaw, K. Roulin, Fabienne Burgat-Charvillon, Delphine Valognes, M. Camps, C. Chabert, C. Gillieron, B. Françon, D. Perrin, D. Leroy, D. Gretener, A. Nichols, P. Vitte, S. Carboni, C. Rommel, M. Schwarz, T. Rückle   +20 more
semanticscholar   +1 more source

Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis

European Journal of Medicinal Chemistry, 2014
Mutasem O Taha, Mahmoud A Al-Sha'er, Mohammad A Khanfar   +2 more
exaly  

Phosphoinositide 3-Kinase-δ,γ Inhibitor for Rheumatoid Arthritis

The Journal of Pharmacology and Experimental Therapeutics, 2014
openaire   +1 more source

The Case of the Vanishing Natrium: Phosphoinositide 3-Kinase Inhibitor Did It!

Journal of the American Society of Nephrology
Lakshna Sankar, Dane Patey, Divine Ribakare   +2 more
openaire   +1 more source

New 1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-2-phenylisoquinoline-1(2H)-ones as Phosphoinositide 3-kinase Inhibitors for Treating Cancer and Other Diseases

Recent Patents on Anti-Cancer Drug Discovery
Surya K De
exaly  

Significance of phosphoinositide 3-kinase inhibitors in advanced breast cancer: a systematic review and meta-analysis

Clinical and Translational Oncology
Mohammad Ahmed Khan, Najmi Abul Kalam
exaly  

A Robust Screen for Inhibitors and Enhancers of Phosphoinositide-3 Kinase (PI3K) Activities by Ratiometric Fluorescence Superquenching

Journal of Biomolecular Screening, 2006
exaly