Results 161 to 170 of about 37,565 (330)

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri, Neda Mohsen‐Pour, Najmeh Salehi, Pardis Ketabi Moghadam, Adel Zeinalpour, Amir Sadeghi, Samira Kalayinia, Nayeralsadat Fatemi   +7 more
wiley   +1 more source

The Inositol Polyphosphate 5-Phosphatase, PIPP, Is a Novel Regulator of Phosphoinositide 3-Kinase-dependent Neurite Elongation

, 2005
Lisa M. Ooms, Clare G. Fedele, Megan V. Astle, Ivan Ivetac, Vanessa Cheung, Richard B. Pearson, Meredith J. Layton, Ariel Forrai, Harshal Nandurkar, Christina A. Mitchell   +9 more
openalex   +2 more sources

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Correction for Oak et al., Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase

, 2009

openalex   +1 more source

Les phosphoinositides [PDF]

médecine/sciences, 2015
Julien Viaud, Bernard Payrastre
openaire   +1 more source

Genetic association of the Phosphoinositide‐3 kinase in schizophrenia and bipolar disorder and interaction with a BDNF gene polymorphism [PDF]

, 2011
Anthony Carrard, Annick Salzmann, Nader Perroud, Jérémie Gafner, Alain Malafosse, Félicien Karege   +5 more
openalex   +1 more source

Multiple forms of p55PIK, a regulatory subunit of phosphoinositide 3-kinase, are generated by alternative initiation of translation [PDF]

, 1999
Xianmin Xia, Ginette Serrero
openalex   +1 more source

Nanoformulated Diacerein Alleviates Hyperlipidemia via Gut Microbiota Modulation In Vivo

Nano Select, EarlyView.
A nanoformulation of diacerein (Nano‐DIA) was fabricated with carboxymethyl cellulose, achieving enhanced solubility and rapid dissolution for alternative anti‐hyperlipidemia therapeutics. Mechanistic studies revealed its in vivo lipid‐lowering efficacy is through metabolite‐mediated and microbiota‐dependent manner, highlighting its dual action on host
Zheng Peng, Yi Yu, Mingyi Chen, Weibin Wu, Chunyan Zhu, Caisheng Wu, Weihua Li, Zehua Liu, Qiang Xie   +8 more
wiley   +1 more source

Splice variant v6 of CD44 (CD44v6); phosphoinositide 3-kinase (PI3K) [PDF]

, 2014

openalex   +1 more source

Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications

ChemistryOpen, EarlyView.
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali, Atif Ali Khan Khalil, Muhammad Saeed Akhtar, Adnan Amin, Wajid Zaman   +4 more
wiley   +1 more source