Results 261 to 270 of about 37,565 (330)

Tobamoviruses CP Proteins Hijack Light‐Induced Protein (NbLIP1) to Promote Viral Replication by Facilitating VRO Formation

Plant Biotechnology Journal, EarlyView.
ABSTRACT Tobamoviruses establish viral replication organelles (VROs) on the host endoplasmic reticulum (ER) for their replication, a process demanding substantial different types of lipids. However, how viruses efficiently transfer these lipids from other compartments like chloroplasts remains incompletely understood.
Haoyu Chen, Mingjie Wu, Xiao Guo, Hongmei Xu, Chenwei Feng, Duxuan Liu, Jing Hua, Yanhong Hua, Zhen He, Peter Moffett, Kun Zhang   +10 more
wiley   +1 more source

Protoplast‐Based Functional Genomics and Genome Editing: Progress, Challenges and Applications

Plant, Cell &Environment, EarlyView.
ABSTRACT Protoplast‐based systems provide a powerful and versatile platform for exploring how plants sense and respond to their environment. By enabling the direct delivery of proteins, DNA, and RNA into plant cells after cell wall removal, this approach facilitates precise molecular dissection of signaling, stress adaptation, and gene regulation ...
Jo‐Wei Allison Hsieh, Fu‐Hui Wu, Dian‐Xuan Yang, Ai‐En Wu, Ching‐Ann Liu, Chang‐Hung Chen, Shinn‐Zong Lin, Ying‐Chung Jimmy Lin, Choun‐Sea Lin   +8 more
wiley   +1 more source

Primary cilia function as hubs for signal transduction. [PDF]

Cell Biosci
Li B, He YY, Yang ZM.
europepmc   +1 more source

Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review

Photochemistry and Photobiology, EarlyView.
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima, Rebeca Barros Nascimento, Ana Paula Mariano Santos Ginez, Maria Stella Moreira, Rebeca Boltes Cecatto, Rodrigo Labat Marcos, Maria Fernanda Setúbal Destro Rodrigues   +6 more
wiley   +1 more source

An effector of phosphatidylinositol 3-kinase activity promotes <i>Rickettsia rickettsii</i> virulence by enhancing autophagy. [PDF]

mBio
Huang D, OuYang X, Peng Z, Chen D, Song L, Luo Z-Q.   +5 more
europepmc   +1 more source

Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors

, 2011
Jesús R. Medina, Christopher Becker, Charles W. Blackledge, Céline Duquenne, Yanhong Feng, Seth W. Grant, Dirk A. Heerding, William Li, William H. Miller, Stuart P. Romeril, D. Scherzer, Arthur Y. L. Shu, Mark A. Bobko, Antony Chadderton, Melissa Dumble, Christine Gardiner, S. Gilbert, Qi Liu, Sridhar K. Rabindran, Valery Sudakin, Hong Xiang, Pat Brady, Nino Campobasso, Paris Ward, Jeffrey M. Axten   +24 more
openalex   +1 more source

Crucial roles of calcium ATPases and phosphoinositides: Insights into pathophysiology and therapeutic strategies. [PDF]

Mol Cells
Gu HO, Noh SW, Kim OH, Oh BC.
europepmc   +1 more source

The therapeutic role of exercise training during menopause for reducing vascular disease

Experimental Physiology, EarlyView.
Abstract Menopause marks a major milestone in female reproductive ageing. It is characterized by the cessation of ovarian function and a concomitant decline in hormones such as oestradiol. Subsequently, females undergoing menopausal transition experience a progressive increase in cardiovascular and cerebrovascular disease risk.
Conan L. H. Shing, Bert Bond, Kerrie L. Moreau, Jeff S. Coombes, Jenna L. Taylor   +4 more
wiley   +1 more source

Muscle wasting in cancer cachexia: Mechanisms and the role of exercise

Experimental Physiology, EarlyView.
Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento, Louisa Tichy, Traci L. Parry   +2 more
wiley   +1 more source

Fighting fire with fire: PLA2G15 inhibition mobilizes BMP lipids to combat NPC1 disease. [PDF]

Metabol Open
Meng W, Liu J, Huang X.
europepmc   +1 more source