Results 281 to 290 of about 37,565 (330)

The link between sarcopenic obesity and Alzheimer's disease: a brain‐derived neurotrophic factor point of view

The Journal of Physiology, EarlyView.
Abstract figure legend A, Sarcopenic obesity is defined as the age‐related loss of skeletal muscle mass and function that often leads to the progression of comorbidities, such as Alzheimer's disease (AD). Though the exact link between the two diseases is unknown, alterations in brain‐derived neurotrophic factor (BDNF) may be a contributor.
Emily N. Copeland, Paul J. LeBlanc, Paula Duarte‐Guterman, Val A. Fajardo, Rebecca E. K. MacPherson   +4 more
wiley   +1 more source

Inositol metabolism as a broad-spectrum antiviral target. [PDF]

Front Microbiol
Jitobaom K, Auewarakul P.
europepmc   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Resolving the two-body problem: A postulated role for the V0 sector of the V0V1-ATPase in exosome biogenesis and multivesicular body fate. [PDF]

Mol Biol Cell
D'Souza-Schorey C, Stahl PD.
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Ionotropic Receptors as Potential Targets Against Insect-Transmitted Diseases. [PDF]

Biomolecules
Pessoa J.
europepmc   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Lipid-lncRNA Crossroads: An Overview of Interactions Between Lipids and lncRNA. [PDF]

Cells
Bayona-Hernandez A, Miladinović A, Antiga L, Hozak P, Sztacho M, Castano E.   +5 more
europepmc   +1 more source

Use of Bio-Layer Interferometry (BLI) to Measure Binding Affinities of SNAREs and Phosphoinositides. [PDF]

Methods Mol Biol
Calderin JD, Zhang C, Tan TJC, Wu NC, Fratti R.   +4 more
europepmc   +1 more source

A phosphoinositide-mediated switch of GET pathway receptor dimerization in Arabidopsis

Lei Zhang, Aron Struß, Mengchun Qin, Annika Dombrowski, Tingting Li, Susanne Viebahn, Dietmar Gerald Mehlhorn, Christopher Grefen   +7 more
openalex   +1 more source