Phospholipase A activity associated with membranes of human polymorphonuclear leucocytes.
Biochemical Journal, 1977 Homogenates of human polymorphonuclear leucocytes (granulocytes) contain a Ca2+-dependent phospholipase A with optimal activity pH7.0. This enzyme is membrane-bound and is enriched in crude cytoplasmic-granule fraction.
R. Franson +4 more
semanticscholar +1 more source
Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells. [PDF]
, 1998 Activation of T and natural killer (NK) cells leads to the tyrosine phosphorylation of pp36 and to its association with several signaling molecules, including phospholipase Cgamma-1 and Grb2.
Berg, SF +8 more
core +1 more source
Snake Venomics and Antivenomics of Bothrops diporus, a Medically Important Pitviper in Northeastern Argentina [PDF]
, 2015 Snake species within genus Bothrops are responsible for more than 80% of the snakebites occurring in South America. The species that cause most envenomings in Argentina, B.
Calvete, Juan J. +3 more
core +2 more sources
The action of phospholipase A on purified phospholipids, plasma and tissue preparations.
Biochemical Journal, 1964 Earlier work in this Laboratory on the action of phospholipase A in aqueous systems indicated that the phospholipase A (phosphatide acyl-hydrolase, EC 3.1.1.4) in human pancreas, unlike the enzyme in snake venom from Cottonmouth moccasin (Agkistrodon ...
S. Ibrahim, H. Sanders, R. Thompson
semanticscholar +1 more source
Breaking the Cycle, Cholesterol Cycling, and Synapse Damage in Response to Amyloid-ß [PDF]
, 2017 Soluble amyloid-β (Aβ) oligomers, a key driver of pathogenesis in Alzheimer disease, bind to cellular prion proteins (PrPC) expressed on synaptosomes resulting in increased cholesterol concentrations, movement of cytoplasmic phospholipase A2 (cPLA2) to ...
Bate, C
core +2 more sources
Phospholipase A in Gram-negative bacteria and its role in pathogenesis.
Microbiology, 2006 Phospholipase A (PLA) is one of the few enzymes present in the outer membrane of Gram-negative bacteria, and is likely to be involved in the membrane disruption processes that occur during host cell invasion.
T. Istivan, P. Coloe
semanticscholar +1 more source
The Effects of Bee Venom on PLA2 and Calcium Concentration in Raw 264.7 Cells
Journal of Pharmacopuncture, 2003 Objectives : The purpose of this study was to investigate the effect of Bee Venom on the lipopolysaccharide, sodium nitroprusside and hydrogen peroxide induced expression phospholipase A2 and calcium concentration in RAW 264.7 cells, a murine macrophage ...
Jong-Il Yun +3 more
doaj +1 more source
The positional specificity of lysosomal phospholipase A activities.
Biochemical Journal, 1967 The presence of phospholipase A in lysosomes of bovine adrenal medulla has recently been reported (Blaschko, Smith, Winkler, van den Bosch & van Deenen, Like many other lysosomal enzymes this phospholipase exhibited highest activity at low pH, the actual
H. Winkler +3 more
semanticscholar +1 more source
On the interactions of lipids and proteins in the red blood cell membrane [PDF]
, 1970 The effects of temperature and of the action of a purified phospholipase C enzyme preparation on human red blood cell membranes has been investigated by chemical analyses, circular dichroism, and proton magnetic resonance measurements.
Chan, Sunney I. +4 more
core
Serumanti-PLA2R antibody predicted treatment outcome in idiopathic membranous nephropathy
Linchuang shenzangbing zazhi, 2021 Objective To explore the predictive value of serum phospholipase A2 receptor antibody in determining the efficacy of rituximab in the treatment of idiopathic membranous nephropathy（IMN）.Methods From August 1,2017 to May 31,2020,a total of 120 IMN ...
Zhang Xue-qin +4 more
doaj