Results 71 to 80 of about 22,854,117 (232)

Stimulated platelets release equivalent amounts of arachidonate from phosphatidylcholine, phosphatidylethanolamine, and inositides.

open access: yesJournal of Lipid Research, 1988
Thrombin-induced changes in arachidonate content of platelet phospholipids were quantitated to establish the ultimate origins of this eicosanoid precursor.
M J Broekman
doaj  

Effect of darapladib treatment on endarterectomy carotid plaque lipoprotein-associated phospholipase A2 activity: a randomized, controlled trial.

open access: yesPLoS ONE, 2014
BackgroundThe aim of this study was to assess the effects of darapladib, a selective oral investigational lipoprotein-associated phospholipase A2 inhibitor, on both plasma and plaque lipoprotein-associated phospholipase A2 activity.MethodsPatients ...
Joel L Johnson   +7 more
doaj   +1 more source

Serine Phospholipid-specific Phospholipase A That Is Secreted from Activated Platelets

open access: yesJournal of Biological Chemistry, 1997
Rat platelets secrete two types of phospholipases upon stimulation; one is type II phospholipase A2 and the other is serine-phospholipid-selective phospholipase A.
Takuji Sato   +7 more
semanticscholar   +1 more source

Lipid vesicle fusion induced by phospholipase C activity in model bile.

open access: yesJournal of Lipid Research, 1993
Using a system of phosphatidylcholine-cholesterol vesicles to model the vesicle phase of mammalian bile (1:1 molar ratio) we evaluated whether very small amounts of C.
TE Little, H Madani, SP Lee, EW Kaler
doaj  

HISTOCHEMICAL STUDIES ON THE LIPID REQUIREMENT FOR THE OXIDATIVE ENZYME ACTIVITIES : III. STUDIES ON THE EFFECTS UPON THE OXIDATIVE ENZYME ACTIVITIES OF PRE-TREATMENT WITH PHOSPHOLIPASES [PDF]

open access: yes, 1965
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。(1) Comparative studies have been made on the inhibitory effects of phaspholipase A, phospholipase C and phospholipase D upon the activities of cytochrome cxidase, DPNH diaphorase, TPNH diaphorase, succinic ...
OHKAWA, Kinichi
core  

Phospholipase Cγ1 (PLCγ1) controls osteoclast numbers via colony-stimulating factor 1 (CSF-1)-dependent diacylglycerol/β-catenin/cyclinD1 pathway [PDF]

open access: yes, 2016
Phospholipases Cγ (PLCγ) 1 and 2 are a class of highly homologous enzymes modulating a variety of cellular pathways through production of inositol 1,4,5-trisphosphate and diacylglycerol (DAG).
Faccio, Roberta   +4 more
core   +2 more sources

Phospholipid metabolism by phagocytic cells. Phospholipases A2 associated with rabbit polymorphonuclear leukocyte granules

open access: yesJournal of Lipid Research, 1974
Polymorphonuclear leukocytes obtained from sterile peritoneal exudates in rabbits contain two phospholipid-splitting activities (phosphatidylacylhydrolases EC 3.1.1.4), one most active at pH 5.5 and the other between pH 7.2 and 9.0.
R. Franson, P. Patriarca, P. Elsbach
doaj  

Pharmacometabolomics reveals racial differences in response to atenolol treatment. [PDF]

open access: yes, 2013
Antihypertensive drugs are among the most commonly prescribed drugs for chronic disease worldwide. The response to antihypertensive drugs varies substantially between individuals and important factors such as race that contribute to this heterogeneity ...
Beitelshees, Amber L   +12 more
core   +2 more sources

Subcellular localization of the phospholipases A of rat heart: evidence for a cytosolic phospholipase A1.

open access: yesJournal of Lipid Research, 1985
During myocardial ischemia increased levels of lysoglycerophospholipids have been reported which may be deleterious to myocardial function. Phospholipases are presumed to be important in the regulation of this process.
G Nalbone, K Y Hostetler
doaj  

The Utility of the Lipoprotein-Associated Phospholipase A (Lp-PLA) Assay in Detecting Abnormalities in Lipid Metabolism and Cardiovascular Risk in an HIV-Infected South African Cohort

open access: yesClinical and Applied Thrombosis/Hemostasis, 2019
People with HIV (PWH) have an increased prevalence of cardiovascular disease (CVD) compared to uninfected patients. Lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) catalyzes the synthesis of pro-inflammatory lipids that recruit monocytes.
Elizabeth S. Mayne MD   +7 more
doaj   +1 more source

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