Pathophysiological changes in the mouth of patients with diabetes mellitus (DM) predispose to overgrowth of Candida albicans. Various virulence factors such as proteinase and phospholipase production are involved in the process of degradation of the host
Faezeh Mohammadi+3 more
doaj
Suramin inhibits the early effects of PLA(2) neurotoxins at mouse neuromuscular junctions: a twitch tension study [PDF]
Several phospholipase A(2) (PLA(2)) neurotoxins from snake venoms can affect acetylcholine release at the neuromuscular junction. In isolated nerve-muscle preparations three distinct phases have been described for this phenomenon: An initial transient ...
Fathi, Behrooz+2 more
core +1 more source
Contact-dependent hemolysins are virulence factors in a number of human pathogens, including Helicobacter pylori, Rickettsia typhi, Bartonella bacilliformis, Mycobacterium tuberculosis, entero-invasive Escherichia coli, and Shigella.
Michael A. Apicella+6 more
doaj +1 more source
The cholesterol ester cycle regulates signalling complexes and synapse damage caused by amyloid-ß [PDF]
Cholesterol is required for the formation and function of some signalling platforms. In synaptosomes, amyloid-β (Aβ) oligomers, the causative agent in Alzheimer's disease, bind to cellular prion proteins (PrPC) resulting in increased cholesterol ...
Anderson+57 more
core +1 more source
Monolysocardiolipin: improved preparation with high yield
A simple, high-yielding preparation of monolysocardiolipin (MLCL) by phospholipase A2 hydrolysis of cardiolipin (CL) in methanol on a semi-preparative scale is described. In methanol, phospholipase A2 preferentially hydrolyzes CL to MLCL.
Junhwan Kim, Charles L. Hoppel
doaj
The structure of the naturally occurring phosphoglycerides. 3. Action of moccasin-venom phospholipase A on ovolecithin and related substances [PDF]
C. Long, I. F. Penny
openalex +1 more source
Background Numerous investigations demonstrate a novel role of thyroid hormone as a modulator of signal transduction. Protein kinase C (PKC) is critical to the mechanism by which thyroid hormones potentiate both the antiviral and immunomodulatory actions
Krasilnikova Oksana A+2 more
doaj +1 more source
The structure of the naturally occurring phosphoglycerides. 4. Action of cabbage-leaf phospholipase D on ovolecithin and related substances [PDF]
Flora M. Davidson, C. Long
openalex +1 more source
Localization of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) expression in mouse brain: A new perspective on N-acylethanolamines as Neural Signaling Molecules [PDF]
The definitive version is available at www3.interscience.wiley ...
Cravatt, BF+3 more
core
Availability of free arachidonic acid (AA) constitutes a rate limiting factor for cellular eicosanoid synthesis. AA distributes differentially across membrane phospholipids, which is largely due to the action of coenzyme A-independent transacylase (CoA ...
Patricia Lebrero+6 more
doaj +1 more source