Results 121 to 130 of about 118,465 (262)

Phospholipase A2 and inflammation. [PDF]

open access: yesAnnals of the Rheumatic Diseases, 1989
P Vadas, W Pruzanski
openaire   +3 more sources

Mechanism(s) of activation of secretory phospholipase A2s in mouse keratinocytes

open access: yesJournal of Lipid Research, 1999
The differential activation of different members of the phospholipase A2 (PLA2) superfamily and their regulation are important as one or more of them regulates the production of eicosanoids and others may contribute to the formation of other lipid ...
Bangyan Li-Stiles, Susan M. Fischer
doaj  

Lithium modifies brain arachidonic and docosahexaenoic metabolism in rat lipopolysaccharide model of neuroinflammation

open access: yesJournal of Lipid Research, 2010
Neuroinflammation, caused by 6 days of intracerebroventricular infusion of a low dose of lipopolysaccharide (LPS; 0.5 ng/h), stimulates brain arachidonic acid (AA) metabolism in rats, but 6 weeks of lithium pretreatment reduces this effect.
Mireille Basselin   +6 more
doaj  

Lipid levels in sperm, eggs, and during fertilization in Xenopus laevis

open access: yesJournal of Lipid Research, 2008
Critical developmental periods, such as fertilization, involve metabolic activation, membrane fusion events such as sperm-egg or plasma membrane-cortical granule merger, and production and hydrolysis of phospholipids.
Douglas W. Petcoff   +2 more
doaj  

Lysophosphatidylcholine induces arachidonic acid release and calcium overload in cardiac myoblastic H9c2 cells

open access: yesJournal of Lipid Research, 1999
Lysophosphatidylcholine (lyso-PC) and arachidonate are products of phosphatidylcholine hydrolysis by phospholipase A2. In this study, the modulation of arachidonate release by exogenous lyso-PC in rat heart myoblastic H9c2 cells was examined.
Leonard S. Golfman   +6 more
doaj  

Identification and Inference with Invalid Instruments [PDF]

open access: yesarXiv
Instrumental variables (IVs) are widely used to study the causal effect of an exposure on an outcome in the presence of unmeasured confounding. IVs require an instrument, a variable that is (A1) associated with the exposure, (A2) has no direct effect on the outcome except through the exposure, and (A3) is not related to unmeasured confounders ...
arxiv  

Regulation of phospholipase A2 activity by different lipid-water interfaces.

open access: hybrid, 1977
Arend J. Slotboom   +2 more
openalex   +1 more source

Phospholipase A2 structure/function, mechanism, and signaling1

open access: yesJournal of Lipid Research, 2009
Tremendous advances in understanding the structure and function of the superfamily of phospholipase A2 (PLA2) enzymes has occurred in the twenty-first century.
John E. Burke, Edward A. Dennis
doaj  

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