Results 41 to 50 of about 59,281 (286)

A2: Mathematical relativity and other progress in classical gravity theory - a session report [PDF]

open access: yesGen Relativ Gravit (2014) 46:1695, 2013
We report on selected oral contributions to the A2 session "Mathematical relativity and other progress in classical gravity theory" of "The 20th International Conference on General Relativity and Gravitation (GR20)" in Warsaw.
arxiv   +1 more source

Separation of variables for A2 Ruijsenaars model and new integral representation for A2 Macdonald polynomials [PDF]

open access: yesJ.Phys.A29:2779-2804,1996, 1996
Using the Baker-Akhiezer function technique we construct a separation of variables for the classical trigonometric 3-particle Ruijsenaars model (relativistic generalization of Calogero-Moser-Sutherland model). In the quantum case, an integral operator M is constructed from the Askey-Wilson contour integral.
arxiv   +1 more source

A Novel 3D High‐Throughput Phenotypic Drug Screening Pipeline to Identify Drugs with Repurposing Potential for the Treatment of Ovarian Cancer

open access: yesAdvanced Healthcare Materials, EarlyView.
Ovarian cancer's high recurrence and therapy resistance demand new strategies. A high‐throughput drug screening pipeline using 3D spheroids, which showed poor concordance with 2D models, identified rapamycin as a promising candidate. In combination with cisplatin, rapamycin demonstrated significant in vitro and in vivo efficacy, highlighting the ...
Nazanin Karimnia   +9 more
wiley   +1 more source

Systemic lupus erythematosus and cardiovascular disease

open access: yesJournal of Internal Medicine, Volume 293, Issue 1, Page 48-62, January 2023., 2023
Abstract The prognosis in systemic lupus erythematosus (SLE) has improved due to better treatment and care, but cardiovascular disease (CVD) still remains an important clinical problem, since the risk of CVD in SLE is much higher than among controls.
Johan Frostegård
wiley   +1 more source

From sound to meaning in the auditory cortex: A neuronal representation and classification analysis [PDF]

open access: yesarXiv, 2023
The neural mechanisms underlying the comprehension of meaningful sounds are yet to be fully understood. While previous research has shown that the auditory cortex can classify auditory stimuli into distinct semantic categories, the specific contributions of the primary (A1) and the secondary auditory cortex (A2) to this process are not well understood.
arxiv  

Accelerated Bone Healing via Electrical Stimulation

open access: yesAdvanced Science, EarlyView.
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun   +4 more
wiley   +1 more source

Exendin-4 protects mitochondria from reactive oxygen species induced apoptosis in pancreatic Beta cells.

open access: yesPLoS ONE, 2013
ObjectiveMitochondrial oxidative stress is the basis for pancreatic β-cell apoptosis and a common pathway for numerous types of damage, including glucotoxicity and lipotoxicity.
Zhen Li   +5 more
doaj   +1 more source

Mannose‐Glycated Metal‐Phenolic Microcapsules Orchestrate Phenotype Switch of Macrophages for Boosting Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
Immunomodulatory metal‐phenolic microcapsules (mMPMs) is developed in this study that leverages dopamine‐modified hyaluronic acid and FeIII assemble on mannose‐glycated bovine serum albumin microbubbles. mMPMs effectively promote macrophage internalization and M1 polarization, enhancing pro‐inflammatory responses.
Xin Tan   +9 more
wiley   +1 more source

Phospholipase A2 Receptor Antibody IgG4 Subclass Improves Sensitivity and Specificity in the Diagnosis of Idiopathic Membranous Nephropathy

open access: yesKidney & Blood Pressure Research, 2019
Aims: The aim of this study was to develop a new method for detecting anti-phospholipase A2 receptor-IgG4 to improve the sensitivity and specificity in the diagnosis of idiopathic membranous nephropathy (IMN).
Biao Huang   +7 more
doaj   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

open access: yesAggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai   +6 more
wiley   +1 more source

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