Results 61 to 70 of about 343,412 (268)

Two unusual cases of PLA2G6-associated neurodegeneration from India

Annals of Indian Academy of Neurology, 2016
Phospholipase A2-associated neurodegeneration (PLAN) comprises of three disorders with overlapping presentations. The most common of these is classical or infantile-onset phospholipase A2-associated neurodegeneration, also known as infantile neuroaxonal ...
Shilpa D Kulkarni, Meenal Garg, Rafat Sayed, Varsha A Patil   +3 more
doaj   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

Apolipoprotein B exhibits phospholipase A1 and phospholipase A2 activities [PDF]

, 1993
Low density lipoproteins (LDL) as well as isolated apolipoprotein B (ApoB) have been shown to exhibit phospholipase A2 (PLA2) activity toward phospholipids containing an oxidized or short fatty acyl chain at position 2. Some of these studies employed the
Arie Dagan, Yedgar, Saul, Nurit Reisfeld, Dov Lichtenberg, Lichtenberg, Dov, Dagan, Arie, Reisfeld, Nurit, Saul Yedgar   +7 more
core   +1 more source

Crosstalk Between Parkinson's Disease and Colorectal Cancer: Genetic Mechanisms, Gut Microbiota, and Therapeutic Insights

Health Care Science, EarlyView.
This review elucidates the crosstalk between Parkinson's disease and colorectal cancer, driven by shared genetics (PRKN, PINK1, DJ‐1) involving oxidative stress, cell cycle regulation, and inflammation. It identifies the gut microbiota—via functional amyloids and short‐chain fatty acids (SCFAs)—as a mechanistic bridge, offering insights for dual ...
Jiacheng Ying, Zhengyuan Fang, Cheng Zhang, Xu Liu, Jianzhi Cui, Zezhi Li, Jiayin Tang   +6 more
wiley   +1 more source

Group II phospholipase A2 induced by interleukin-1β in cultured rat gingival fibroblasts [PDF]

, 1992
Previously, we reported the presence of group II-like phospholipase A2 activity in the soluble fraction of rat gingiva. In the present study, we found that treatment of rat gingival cells with human recombinant interleukin- 1β resulted in dose-dependent ...
Tojo, Hiromasa, Hiroyuki Shinohara, Takanori Komatsubara, Yoichi Wakano, Shinohara, Hiroyuki, Okamoto, Mitsuhiro, Komatsubara, Takanori, Wakano, Yoichi, Hiromasa Tojo, Hiroshi Ishida, Mitsuhiro Okamoto, Ishida, Hiroshi, Amabe, Yukari, Yukari Amabe   +13 more
core   +1 more source

Neural epidermal growth factor-like 1 expression predicts end-stage renal disease in phospholipase A2 receptor–negative membranous nephropathy: A retrospective cohort stratified by systemic lupus erythematosus

Journal of International Medical Research
Background Neural epidermal growth factor-like 1 protein has emerged as a significant antigen in membranous nephropathy, an important cause of nephrotic syndrome in adults.
Qingqing Rao, Yuan Cheng, Shuling Yue, Haiying Song, Wangyang Li, Dongli Qi, Qijun Wan   +6 more
doaj   +1 more source

Differential determination of phospholipase A2 and PAF-acetylhydrolase in biological fluids using fluorescent substrates

Journal of Lipid Research, 1999
The purpose of the present study was the development and evaluation of a fluorimetric method for the screening and differential determination of phospholipase A2 and PAF-acetylhydrolase in bronchoalveolar lavage (BAL) fluid and serum.
Eirini I. Kitsiouli, George Nakos, Marilena E. Lekka   +2 more
doaj   +1 more source

Phospholipase A2 and Phospholipase B activities in fungi [PDF]

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2006
As saprophytes or disease causing microorganisms, fungi acquire nutrients from dead organic material or living host organisms. Lipids as structural components of cell membranes and storage compartments play an important role as energy-rich food source.
Gerwald A, Köhler, Audrey, Brenot, Eric, Haas-Stapleton, Nina, Agabian, Rupal, Deva, Santosh, Nigam   +5 more
openaire   +2 more sources

Phospholipase A2 Activates Hemostasis

Drug Target Insights, 2007
Background: Phospholipases A2 (PLA2) are aggressive enzymes that can destroy phospholipids of cell membranes. The resulting cell fragments trigger the kallikrein—mediated contact phase of coagulation.
Thomas W. Stief
doaj  

Structure of Porcine Pancreatic Phospholipase A2 at 2.6 Å Resolution and Comparison with Bovine Phospholipase A2

, 1983
The previously published three-dimensional structure of porcine pancreatic prophospholipase A2 at 3 Å resolution was found to be incompatible with the structures of bovine phospholipase A2 and bovine prophospholipase A2.
Kalk, Kor H., Drenth, Jan, Hol, Wim G.J., Dijkstra, Bauke W., Renetseder, Roland   +4 more
core   +1 more source