Results 221 to 230 of about 255,660 (330)

Generation of inositol polyphosphates through a phospholipase C-independent pathway involving carbohydrate and sphingolipid metabolism in <i>Trypanosoma cruzi</i>. [PDF]

mBio
Bertolini MS, Cline SE, Chiurillo MA, Mantilla BS, Eidex A, Crowe LP, Qiu D, Jessen HJ, Saiardi A, Docampo R.   +9 more
europepmc   +1 more source

Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer's disease. [PDF]

Immunity, 2023
Tsai AP, Dong C, Lin PB, Oblak AL, Viana Di Prisco G, Wang N, Hajicek N, Carr AJ, Lendy EK, Hahn O, Atkins M, Foltz AG, Patel J, Xu G, Moutinho M, Sondek J, Zhang Q, Mesecar AD, Liu Y, Atwood BK, Wyss-Coray T, Nho K, Bissel SJ, Lamb BT, Landreth GE.   +24 more
europepmc   +1 more source

Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids

Movement Disorders, EarlyView.
Abstract Neurodegenerative diseases are pathological states characterized by progressive alterations in brain homeostasis during aging. Synucleinopathies, including Parkinson's disease and dementia with Lewy bodies, are defined neuropathologically by the accumulation of inclusions known as Lewy bodies and Lewy neurites.
Manuel Flores‐León, Tiago F. Outeiro
wiley   +1 more source

Fundamental Role for Sperm Phospholipase C ζ in Mammalian Fertilization

, 2017
Michail Nomikos, Karl Swann, F. Anthony Lai   +2 more
openalex   +2 more sources

T‐Cell Signaling Pathways, Including Exhaustion, Predominate in Unhealthy Visceral and Subcutaneous Adipose Tissues

Obesity, EarlyView.
ABSTRACT Objective Obesity is an imperfect correlate of metabolic health. Visceral adipose tissue (VAT) characteristics are considered determinants of poor health and subcutaneous adipose tissue (SAT) considered protective. There is a gap in knowledge regarding shared vs.
Sobha Puppala, Alyssa R. Hamann, Christina M. Stevens, Alistaire Ruggiero, Laura A. Cox, Kylie Kavanagh   +5 more
wiley   +1 more source

U-73122, a phospholipase C inhibitor, impairs lymphocytic choriomeningitis virus virion infectivity. [PDF]

J Gen Virol
Mizuma K, Hashizume M, Urata S, Shindo K, Takashima A, Mizuta S, Iwasaki M.   +6 more
europepmc   +1 more source

Involvement of Phospholipase C in Photosynthesis and Growth of Maize Seedlings. [PDF]

Genes (Basel), 2022
Wei Y, Liu X, Ge S, Zhang H, Che X, Liu S, Liu D, Li H, Gu X, He L, Li Z, Xu J.   +11 more
europepmc   +1 more source

The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy

Pediatric Investigation, EarlyView.
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie, Qian Zhou, Jianxiang Liao, Yuejie Zheng, Wenjian Wang, Kunling Shen   +5 more
wiley   +1 more source

A fungal phospholipase C involved in the degradation of plant glycosylinositol phosphorylceramides during Arabidopsis/Botrytis interaction. [PDF]

Commun Biol
Lelas L, Rouffet J, Filachet A, Sechet J, Davière A, Desprez T, Vernhettes S, Voxeur A.   +7 more
europepmc   +1 more source

Phospholipase C-ε defines a PACAP-stimulated pathway for secretion in the chromaffin cell. [PDF]

J Neuroendocrinol, 2023
Chen X, Coffman BL, Brindley RL, Galpin JD, Ahern CA, Currie KPM, Smrcka AV, Axelrod D, Anantharam A.   +8 more
europepmc   +1 more source