Revista da Sociedade Brasileira de Medicina Tropical, 2013 Introduction Candida albicans is a commensal and opportunistic agent that causes infection in immunocompromised individuals. Several attributes contribute to the virulence and pathogenicity of this yeast, including the production of germ tubes (GTs) and ...
Antonella Souza Mattei +5 more
doaj +1 more source
HISTOCHEMICAL STUDIES ON THE LIPID REQUIREMENT FOR THE OXIDATIVE ENZYME ACTIVITIES : III. STUDIES ON THE EFFECTS UPON THE OXIDATIVE ENZYME ACTIVITIES OF PRE-TREATMENT WITH PHOSPHOLIPASES [PDF]
, 1965 この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。(1) Comparative studies have been made on the inhibitory effects of phaspholipase A, phospholipase C and phospholipase D upon the activities of cytochrome cxidase, DPNH diaphorase, TPNH diaphorase, succinic ...
OHKAWA, Kinichi
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Ezrin-related phosphoinositide pathway modifies RhoA and Rac1 in human osteosarcoma cell lines [PDF]
, 2015 Selected Phosphoinositide-specific Phospholipase C (PI-PLC) enzymes occupy the convergence point of the broad range of pathways that promote Rho and Ras GTPase mediated signalling, which also regulate the activation of ezrin, a member of the ezrin ...
DELLA ROCCA, Carlo +2 more
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Calcium in Renal Cells. Modulation of Calcium-dependent Activation of Phospholipase \(A_2\). [PDF]
, 2011 Calcium has been implicated as a regulatory factor in many physiological and pathophysiological processes in the renal cell. Under physiological conditions, the cytosolic free calcium concentration is maintained at approximately 100 nM.
Bonventre, Joseph Vincent
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Substrate-Specific Inhibition Constants for Phospholipase A2 Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics. [PDF]
, 2019 Assaying lipolytic enzymes is extremely challenging because they act on water-insoluble lipid substrates, which are normally components of micelles, vesicles, and cellular membranes.
Armando, Aaron +2 more
core +6 more sources
Aspirin inhibits phospholipase C
Biochemical and Biophysical Research Communications, 1986 We have shown previously that aspirin (ASA) ingestion by normal human volunteers inhibits peripheral blood monocyte phospholipase C (PLC) activities ex vivo. In order to explore further the mechanism of action of ASA, normal human monocytes and differentiated human U937 cells were treated with ASA and other salicylates. Cells preincubated with ASA were
J S, Bomalaski, F, Hirata, M A, Clark
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Phosphoinositide-specific phospholipase C in health and disease
Journal of Lipid Research, 2015 Phospholipases are widely occurring and can be found in several different organisms, including bacteria, yeast, plants, animals, and viruses. Phospholipase C (PLC) is a class of phospholipases that cleaves phospholipids on the diacylglycerol (DAG) side ...
Lucio Cocco +3 more
doaj +1 more source
Candida albicans isolates from a Malaysian hospital exhibit more potent phospholipase and haemolysin activities than non-albicans Candida isolates [PDF]
, 2013 This study was aimed at determining the phospholipase and haemolysin activity of Candida isolates in Malaysia. A total of 37 Candida clinical isolates representing seven species, Candida albicans (12), Candida tropicalis (8), Candida glabrata (4 ...
Abdullah, Maha +6 more
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