Results 71 to 80 of about 19,781,572 (286)

Regulation of phosphoinositide-specific phospholipase C.

open access: yesAnnual Review of Biochemistry, 2001
S. Rhee
semanticscholar   +1 more source

The Inner Nuclear Membrane Has a Unique Lipid Signature

open access: yesBioEssays, EarlyView.
The inner nuclear membrane (INM) has a distinct lipid profile, most notably characterized by high enrichment of phosphatidylserine (PS). In this review, Yang Niu and Tamas Balla summarize recent advances in elucidating the INM's lipid composition and related metabolic pathways, while elaborating further on their potential functional roles.
Yang Niu, Tamas Balla
wiley   +1 more source

Phospholipase C-γ as a Potential Therapeutic Target for Graves' Orbitopathy. [PDF]

open access: yesEndocrinol Metab (Seoul), 2023
Roh TH   +5 more
europepmc   +1 more source

All Organisms Can Be Anesthetized, but There's No Point?

open access: yesBioEssays, EarlyView.
ABSTRACT Because of their interest in medicine, most studies on anesthesia have historically focused on the nervous systems of animals. This has often led to the neglect of the fact that all life forms have the potential to be anesthetized. Anesthetics target proteins, such as four‐domain voltage‐dependent Na+/Ca2⁺ channels (4D‐NaV/CaV) and glutamate ...
Lucia Sylvain‐Bonfanti   +7 more
wiley   +1 more source

Host Cell Protein Clinical Safety Risk Assessment—An Updated Industry Review

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Host cell proteins (HCP) are process‐related impurities that can co‐purify with therapeutic proteins. Some HCP impurities potentially can have an impact on patient safety (immunogenicity or toxicity), efficacy, and/or product quality. It is important to reduce the levels of HCP impurities with a well‐controlled manufacturing process and to ...
Lisette Coye   +19 more
wiley   +1 more source

A possible role of phospholipase C and phospholipase D in chemotaxis

open access: yesPediatric Dental Journal, 2004
Abstract Cell chemotaxis plays a role in many cellular or individual actions suited to accomplishing a variety of purposes. These actions include activities of bacteria and Protista , cellular slime molds' migration to food, starvationinduced aggregation of cellular slime molds and mobilization of immunocytes to infectious or inflammatory sites
openaire   +3 more sources

Regulation and physiological functions of mammalian phospholipase C.

open access: yesJournal of Biochemistry (Tokyo), 2017
Yoshikazu Nakamura, K. Fukami
semanticscholar   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

open access: yesBMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu   +9 more
wiley   +1 more source

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