Results 81 to 90 of about 19,781,572 (286)
Use of LC‐MS to characterize host cell protein removal during depth filtration
Biotechnology Progress, EarlyView.Abstract The removal of host cell proteins (HCPs) is crucial in biopharmaceutical production, as residual impurities can impact product safety and efficacy. While a number of studies have demonstrated that depth filtration can provide significant HCP removal, there is little information on its effectiveness in removing specific HCPs.
Liang‐Kai Chu +3 more
wiley +1 more source
Chemistry &Biodiversity, EarlyView.Involvement of Ca2+ channels in boldine‐induced vascular relaxation. ABSTRACT The regulation of vascular tone plays a fundamental role in blood pressure homeostasis and still represents a significant challenge in clinical practice. Boldine, a naturally occurring alkaloid from Peumus boldus, has emerged as a compound of interest due to its therapeutic ...
Martina Odebrecht Cavichiolo +3 more
wiley +1 more source
Improved rubella hemagglutination inhibtion test: inactivation of non-immunoglobulin hemagglutination inhibitors by phospholipase C [PDF]
, 1976 Satoru Iwasa, Mayuko Hori
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Endocrinology and Metabolism, 2012 배경: 세포 내 신호전달에 중요한 단백질인 포스포리파제 C-β4(phospholipase C-β4, PLC-β4)의 물리화학적 성질을 연구하기 위해서는 다량의 정제된 단백질이 필요하나 기존의 망막 조직을 이용한 정제 방법은 그 방법이 매우 어려워 충분한 양의 단백질을 정제하는 것이 거의 불가능하다. 따라서 이를 쉽게 정제하기 위하여 배큘로바이러스(baculovirus)를 이용한 발현 및 정제 방법을 개발할 필요가 있다. 또한 배큘로바이러스를 이용한 정제 방법이 확립된 경우 이를 이용하여 키메라 단백질의 발현도 쉽게 할 수 있어 단백질의 성질연구에 매우 유용하다.
openaire +2 more sources
Epigenetic Changes Related to Hypertension in Asian Adults: A Systematic Review
Chronic Diseases and Translational Medicine, EarlyView.PRISMA study flow diagram. ABSTRACT Background Elevated high blood pressure is controlled by complicated, little‐understood genetic and epigenetic pathways that are influenced by both heritable and environmental variables. Many adult systolic and diastolic blood pressure‐related genomic loci have been identified through previous genome‐wide association
Lilik Sukesi +7 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Detergent design parameters determine experimental successes in membrane protein research. Recent progresses in detergent chemistry are reviewed to promote the top‐down design of non‐ionic detergents for the purification and analysis of intact membrane proteins, including lipid interactions.
Katharina Alker +2 more
wiley +1 more source
Influence of phospholipase C on some electrical properties of the skeletal muscle membrane
, 1967 Edson X. Albuquerque, S. Thesleff
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Hydrolysis of Phospholipids by phospholipase C in intact cells of wild‐type and envelope mutants of Escherichia coli K12 [PDF]
, 1981 Zdena Stárková +2 more
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Chemistry – A European Journal, EarlyView.The first experimental identification of the IG head structure of naturally occurring plant GIPCs in Brassicaceae was achieved through the chemical synthesis of three hexose‐type IGs containing d‐glucose, d‐galactose, or d‐mannose as the second monosaccharide linked to d‐glucuronic acid‐α(1→2)‐myo‐inositol.
Yuta Umemura +11 more
wiley +1 more source
The effect of digestion with phospholipase C on intrinsic protein phosphorylation in synaptic plasma membrane fragments [PDF]
, 1982 Ayṣe Döṣemeci, Richard Rodnight
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