Phospholipase D regulates ferroptosis signal transduction in mouse spleen hypoxia response [PDF]
Brazilian Journal of Medical and Biological ResearchHigh-altitude hypoxia exposure can lead to phospholipase D-mediated lipid metabolism disorder in spleen tissues and induce ferroptosis. Nonetheless, the key genes underlying hypoxia-induced splenic phospholipase D and the ferroptosis pathway remain ...
Jiayang Wang +7 more
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Brown Spider Venom Phospholipase-D Activity upon Different Lipid Substrates [PDF]
Toxins, 2023 Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D isoforms, which interact with different cellular membrane components, degrade ...
Daniele Chaves-Moreira +9 more
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Switching the substrate specificity of lysoplasmalogen‐specific phospholipase D [PDF]
FEBS Open Bio, 2021 Lysoplasmalogen‐specific phospholipase D (LyPls‐PLD) catalyzes reactions in a manner similar to those catalyzed by glycerophosphodiester phosphodiesterase (GDPD) and other well‐known PLDs.
Takayuki Oyama +2 more
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Generation of choline for acetylcholine synthesis by phospholipase D isoforms [PDF]
BMC Neuroscience, 2001 Dedication This article is dedicated to the memory of Sue Kim Hanson, a graduate student in the department of Pathology and Laboratory Medicine at Boston University School of Medicine, who perished in the terrorist attacks of September 11, 2001 ...
Blusztajn Jan +2 more
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Role of phospholipase D in the lifespan of Caenorhabditis elegans [PDF]
Experimental and Molecular Medicine, 2018 Aging: Cleaning up the metabolic mess The protein phospholipase D (PLD) is involved in preventing the appearance of signs of aging and prolonging lifespan.
Jeong-Hwan Park +5 more
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Phospholipase D and Choline Metabolism. [PDF]
Handb Exp Pharmacol, 2020 Phospholipases D (PLDs) catalyze hydrolysis of the diester bond of phospholipids to generate phosphatidic acid and the free lipid headgroup. In mammals, PLD enzymes comprise the intracellular enzymes PLD1 and PLD2 and possibly the proteins encoded by related genes, as well as a class of cell surface and secreted enzymes with structural homology to ...
Onono FO, Morris AJ.
europepmc +4 more sources
Toxicological Characterization and Phospholipase D Activity of the Venom of the Spider Sicarius thomisoides. [PDF]
Toxins (Basel), 2020 Arán-Sekul T +7 more
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Whole-Cell Display of Phospholipase D in Escherichia coli for High-Efficiency Extracellular Phosphatidylserine Production. [PDF]
BiomoleculesSun B +6 more
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Characteristics of Phospholipase D and Application in the Synthesis of Phosphatidylserine
Shipin gongye ke-ji, 2022 Phosphatidylserine (PS) is a new resource food, which has less content in nature and the difficulty of extraction. Phospholipase D (PLD) is the critical synthetase in enzymatic preparation of PS.
Bishan GUO +7 more
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Foods, 2022 Phosphatidylserine (PS) was shown to work synergistically with tocopherols to extend the shelf life of oil-in-water emulsions. However, the high cost of PS prevents it from being used as a food additive. This work investigated the potential use of a high-
Harshika Arora +2 more
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