Phospholipase D regulates ferroptosis signal transduction in mouse spleen hypoxia response [PDF]
Brazilian Journal of Medical and Biological ResearchHigh-altitude hypoxia exposure can lead to phospholipase D-mediated lipid metabolism disorder in spleen tissues and induce ferroptosis. Nonetheless, the key genes underlying hypoxia-induced splenic phospholipase D and the ferroptosis pathway remain ...
Jiayang Wang +7 more
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Brown Spider Venom Phospholipase-D Activity upon Different Lipid Substrates [PDF]
Toxins, 2023 Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D isoforms, which interact with different cellular membrane components, degrade ...
Daniele Chaves-Moreira +9 more
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Switching the substrate specificity of lysoplasmalogen‐specific phospholipase D [PDF]
FEBS Open Bio, 2021 Lysoplasmalogen‐specific phospholipase D (LyPls‐PLD) catalyzes reactions in a manner similar to those catalyzed by glycerophosphodiester phosphodiesterase (GDPD) and other well‐known PLDs.
Takayuki Oyama +2 more
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Phospholipase D: emerging therapeutic targets in signaling, metabolism, and immune-oncology [PDF]
Cell Communication and SignalingThe phospholipase D (PLD) family, comprising six evolutionarily conserved isoforms (PLD1-6), serves as master regulators of lipid signaling, membrane dynamics, and cellular communication.
Lin Tang +6 more
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Phospholipase D and Choline Metabolism. [PDF]
Handb Exp Pharmacol, 2020 Phospholipases D (PLDs) catalyze hydrolysis of the diester bond of phospholipids to generate phosphatidic acid and the free lipid headgroup. In mammals, PLD enzymes comprise the intracellular enzymes PLD1 and PLD2 and possibly the proteins encoded by related genes, as well as a class of cell surface and secreted enzymes with structural homology to ...
Onono FO, Morris AJ.
europepmc +4 more sources
Characteristics of Phospholipase D and Application in the Synthesis of Phosphatidylserine
Shipin gongye ke-ji, 2022 Phosphatidylserine (PS) is a new resource food, which has less content in nature and the difficulty of extraction. Phospholipase D (PLD) is the critical synthetase in enzymatic preparation of PS.
Bishan GUO +7 more
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Foods, 2022 Phosphatidylserine (PS) was shown to work synergistically with tocopherols to extend the shelf life of oil-in-water emulsions. However, the high cost of PS prevents it from being used as a food additive. This work investigated the potential use of a high-
Harshika Arora +2 more
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Phosphatidic acid production regulated by receptors with liganddependent tyrosine kinase activity
Grasas y Aceites, 1995 The present study deals with the most recent and important studies on the relationship between transmembrane receptors with ligand-dependent tyrosine kinase activity and cellular lipid metabolism, predominantly in generating phosphatidic acid (PA) as a ...
Fco. J. G. Muriana, V. Ruiz-Gutiérrez
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An amphitropic cAMP-binding protein in yeast mitochondria [PDF]
, 1989 : We describe the first example of a mitochondrial protein with a covalently attached phos-phatidylinositol moiety acting as a membrane anchor. The protein can be metabolically labeled with both stearic acid and inositol.
Bandlow W. +43 more
core +3 more sources
Phosphatides content in soybean oil in function of bean moisture content-at-harvest and storage-time
Grasas y Aceites, 2002 The influence of soybean moisture content-at-harvest and storage time upon total and non-hydratable phosphatides content in oil and bean phospholipase D activity was evaluated.
Enzo A. Tosi +3 more
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