Increased hepatic PAFR expression in MASLD is associated with histological disease severity and may contribute to progression through platelet activation, whereas circulating Lp‐PLA2 levels lack discriminatory value as a noninvasive biomarker. ABSTRACT Objective This study aimed to investigate the platelet‐activating factor (PAF) pathway in obesity ...
Joan Duran‐Bertran +11 more
wiley +1 more source
Luminal Phospholipase D Attacks Bacterial Membranes in Dictyostelium discoideum Phagosomes. [PDF]
Lamrabet O +6 more
europepmc +1 more source
A secretory phospholipase D hydrolyzes phosphatidylcholine to suppress rice heading time. [PDF]
Qu L, Chu YJ, Lin WH, Xue HW.
europepmc +1 more source
ABSTRACT Objective Amnioinfusions in anhydramnios aim to promote fetal lung development, but currently used fluids (Normal Saline [NS], Lactated Ringer's [LR]) fail to mimic the intrauterine environment and increase reactive oxygen species (ROS). We developed a synthetic amniotic fluid (Amnio‐well, AW) designed to reduce intrauterine ROS.
Braxton Forde +3 more
wiley +1 more source
Safety evaluation of the food enzyme phospholipase D from the non-genetically modified <i>Streptomyces netropsis</i> strain DSM 40093. [PDF]
EFSA Panel on Food Enzymes (FEZ) +17 more
europepmc +1 more source
Genome-wide identification and expression analysis of phospholipase D gene in leaves of sorghum in response to abiotic stresses. [PDF]
Wei J +6 more
europepmc +1 more source
The phospholipase iPLA2γ is a major mediator releasing oxidized aliphatic chains from cardiolipin, integrating mitochondrial bioenergetics and signaling [PDF]
Gross, Richard W +6 more
core +2 more sources
From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu +5 more
wiley +1 more source
Corynebacterium pseudotuberculosis phospholipase D targets mitochondrial sphingomyelin and induces NLRP3-GSDMD axis-mediated pyroptosis in macrophages to promote infection. [PDF]
Li X +12 more
europepmc +1 more source
Improving Both the Thermostability and Catalytic Efficiency of Phospholipase D from Moritella sp. JT01 through Disulfide Bond Engineering Strategy. [PDF]
Li L, Mao X, Deng F, Wang Y, Wang F.
europepmc +1 more source

