Results 21 to 30 of about 108,655 (245)
Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Arcanobacterium haemolyticum phospholipase D is genetically and functionally similar to Corynebacterium pseudotuberculosis phospholipase D [PDF]
Infection and Immunity, 1993 Arcanobacterium haemolyticum, a pathogen of the human upper respiratory tract and other systems, has been reported to produce soluble toxins, including a phospholipase D (PLD). We confirmed production of PLD by this organism and cloned and sequenced pld.
J G Songer, W A Cuevas
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee +9 more
wiley +1 more source
The Role of Phospholipase D in Regulated Exocytosis [PDF]
Journal of Biological Chemistry, 2015 There are a diversity of interpretations concerning the possible roles of phospholipase D and its biologically active product phosphatidic acid in the late, Ca(2+)-triggered steps of regulated exocytosis. To quantitatively address functional and molecular aspects of the involvement of phospholipase D-derived phosphatidic acid in regulated exocytosis ...
Rogasevskaia, Tatiana P. +1 more
openaire +4 more sources
Piezoelectric Biomaterials for Bone Regeneration: Roadmap from Dipole to Osteogenesis
Advanced Science, EarlyView.Piezoelectric biomaterials convert mechanical forces into electrical signals, offering novel strategies to restore and modulate bone microenvironments for tissue engineering. This review examines molecular dipole origins, spatial arrangements, and pseudo‐piezoelectric mechanisms and highlights dipole‐engineering techniques for osteogenesis regulation ...
Xiyao Ni +7 more
wiley +1 more source
Cytokine Storm Induction Linked to Multi‐Organ Failure in Fatal Jellyfish Stings
Advanced Science, EarlyView.N. nomurai is the most important injurious species in the coastal area of China. Model construction, omics analysis, mechanism exploration, and intervention measures of N. nomurai envenomation are performed in the current study, and it suggested that cytokine storm played an important role in pathogenesis.
Yichao Wang +15 more
wiley +1 more source
Research Progress on Biomaterials with Immunomodulatory Effects in Bone Regeneration
Advanced Science, EarlyView.This review highlights recent advanced in immunomodulatory biomaterials for bone repair, focusing on design strategies, immune interactions, and clinical potential. Abstract The immune system plays a pivotal role in bone regeneration, and biomaterials engineered to modulate immune responses present a promising strategy for the treatment of extensive ...
Jianan Li +11 more
wiley +1 more source
Engineered Probiotic‐Powered Micro‐Rod Robot Bomb for Thrombus‐Penetrating Explosion
Advanced Science, EarlyView.For thrombotic diseases with narrow therapeutic windows and persistent vascular damage; existing thrombolytic drugs are difficult to achieve precise; timely; and sustained thrombolytic effects. Here an engineered probiotic driven micro‐rod robot for targeted and penetrative treatment for thrombus is developed.
Riyue Liu +8 more
wiley +1 more source
PFKFB2‐Driven Glycolysis Promotes Dendritic Cell Maturation and Exacerbates Acute Lung Injury
Advanced Science, EarlyView.Paraquat (PQ) or lipopolysaccharide (LPS) exposure activates the HIF‐1α–PFKFB2 pathway, driving glycolysis in dendritic cells (DCs). This metabolic shift enhances DC maturation and immune activation, exacerbating acute lung injury (ALI). This study demonstrates that PFKFB2‐driven glycolytic reprogramming in DCs plays a critical role in the pathogenesis
Ding Yuan +17 more
wiley +1 more source
Advanced Science, EarlyView.A novel RBC indicator, ESI, is better than the traditional RBC indicators and is associated with CHF prevalence and in‐hospital death. RBC membrane lipidomics, Cer 18:0;O2/16:0, and LPE 18:0, are associated with plasma volume overload and MACE in CHF patients, but these plasma lipids could not.
Lin Zhang +12 more
wiley +1 more source