Results 21 to 30 of about 116,973 (287)

Crystal Structures of the Plant Phospholipase A1 Proteins Reveal a Unique Dimerization Domain

open access: yesMolecules, 2022
Phospholipase is an enzyme that hydrolyzes various phospholipid substrates at specific ester bonds and plays important roles such as membrane remodeling, as digestive enzymes, and the regulation of cellular mechanism.
Yunseok Heo   +8 more
doaj   +1 more source

PTEN regulates phospholipase D and phospholipase C [PDF]

open access: yesHuman Molecular Genetics, 2007
PTEN is an ubiquitously expressed tumor suppressor which plays a prominent role in the pathogenesis of many types of sporadic solid tumors, including breast cancer, as well as hematologic malignancies. Germline PTEN mutations cause 85% of Cowden syndrome (CS), characterized by a high risk of breast and thyroid cancers, and 65% of Bannayan-Riley ...
Christopher A, Alvarez-Breckenridge   +2 more
openaire   +2 more sources

Molecular diversity of phospholipase D in angiosperms

open access: yesBMC Genomics, 2002
Background The phospholipase D (PLD) family has been identified in plants by recent molecular studies, fostered by the emerging importance of plant PLDs in stress physiology and signal transduction.
Cvrčková Fatima   +3 more
doaj   +1 more source

Nuclear inositides

open access: yesEuropean Journal of Histochemistry, 2009
DAG, 1,2-diacylglycerol; EGF, epidermal growth factor; TNF, tumour necrosis factor; IGF-I, insulinlike growth factor I; Ins(n)P, inositol phosphate; Ins(n,n)P2, inositol bisphosphate; Ins(n,n,n)P3, inositol trisphosphate; MEL, murine erythroleukemia ...
C D'Santos   +4 more
doaj   +3 more sources

Phosphatidic acid: a lipid regulator of the Hippo pathway

open access: yesMolecular & Cellular Oncology, 2019
The Hippo pathway, a signaling pathway highly conserved across species, plays a crucial role in organ size control and cancer suppression. Our recent study shows that phosphatidic acid can regulate the Hippo pathway through a physical lipid-protein ...
Han Han   +3 more
doaj   +1 more source

Characteristics and Lethality of a Novel Recombinant  Dermonecrotic Venom Phospholipase D from  Hemiscorpius lepturus

open access: yesToxins, 2017
Hemoscorpius lepturus is the most medically important scorpion in Iran. The clinical signs of H. lepturus envenomation are remarkably similar to those reported for brown spiders, including dermonecrosis, hematuria, renal failure and even death.
Elham Torabi   +7 more
doaj   +1 more source

Recent Advances in the Cellular and Developmental Biology of Phospholipases in Plants

open access: yesFrontiers in Plant Science, 2019
Phospholipases (PLs) are lipid-hydrolyzing enzymes known to have diverse signaling roles during plant abiotic and biotic stress responses. They catalyze lipid remodeling, which is required to generate rapid responses of plants to environmental cues ...
Tomáš Takáč   +2 more
doaj   +1 more source

Effect of GM2 activator protein on the enzymatic hydrolysis of phospholipids and sphingomyelin

open access: yesJournal of Lipid Research, 2003
GM2 activator protein (GM2AP) is a specific protein cofactor that stimulates the enzymatic hydrolysis of the GalNAc from GM2, a sialic acid containing glycosphingolipid, both in vitro and in lysosomes. While phospholipids together with glycosphingolipids
Yoshimi Shimada, Yu-Teh Li, Su-Chen Li
doaj   +1 more source

Identification and Expression Analysis of the Phospholipase D Gene Family in Rice

open access: yesGuangdong nongye kexue
【Objective】Phospholipase D (PLD) plays a crucial role in plant growth, development, and stress response. The study was conducted to explore the PLD gene family members involved in biotic and abiotic stress in rice (Oryza sativa L.) and investigate their ...
Huasheng CAO   +8 more
doaj   +1 more source

Changes in Lipase and Antioxidant Enzyme Activities during Processing of Cantonese Sausage with D-Sodium Erythorbate

open access: yesJournal of Food Quality, 2019
Pork was used as raw material to produce Cantonese sausage, with additions of 0.05% or 0.1% D-sodium erythorbate. The oxidation indices (peroxide value, TBARS value, carbonyl value, and conjugated dienes value) and enzyme activity (total phospholipase ...
Xiaolan Shang, Jie Qiao, Zhanxiong Chen
doaj   +1 more source

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