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Search for and functional annotation of multi-domain PLA2 family proteins in flatworms
Вавиловский журнал генетики и селекцииThe phospholipase A2 (PLA2) is a superfamily of hydrolases that catalyze the hydrolysis of phospholipids and play a key role in many molecular processes in the cells and the organism as a whole.
M. E. Bocharnikova +2 more
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Frontiers in Plant Science, 2023 The lignification of plant secondary walls is an important process that provides plants with mechanical support. However, the presence of lignin in the secondary walls affects the readily availability of cellulose required in various industries ...
David Charles Simiyu +6 more
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Biomédica: revista del Instituto Nacional de Salud, 2022 Introducción. Las proteasas y las fosfolipasas son factores de virulencia de Candida spp. que cumplen un papel importante en la invasión de los tejidos.
Martha Puello +2 more
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The PNPLA family of enzymes: characterisation and biological role
Arhiv za Higijenu Rada i Toksikologiju, 2023 This paper brings a brief review of the human patatin-like phospholipase domain-containing protein (PNPLA) family. Even though it consists of only nine members, their physiological roles and mechanisms of their catalytic activity are not fully understood.
Lulić Ana-Marija, Katalinić Maja
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Functional Modulation of Human Macrophages by Secreted Phospholipases A2: Implications in Cancer
Biomedicines, 2022 Cancer-related inflammation has recently emerged as an important component of cancer pathogenesis that is able to promote tumor initiation and progression, and the acquisition of the known hallmark capabilities, including evasion from immunosurveillance.
Maria Rosaria Galdiero +9 more
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Phospholipases A and Lysophospholipases in protozoan parasites
Microbial Cell, 2023 Phospholipases (PLs) and Lysophospholipases (LysoPLs) are a diverse group of esterases responsible for phospholipid or lysophospholipid hydrolysis. They are involved in several biological processes, including lipid catabolism, modulation of the immune ...
Perrine Hervé +3 more
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Phospholipases C and D and Their Role in Biotic and Abiotic Stresses
Plants, 2021 Plants, as sessile organisms, have adapted a fine sensing system to monitor environmental changes, therefore allowing the regulation of their responses. As the interaction between plants and environmental changes begins at the surface, these changes are ...
Víctor M. González-Mendoza +3 more
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International Journal of Molecular Sciences, 2011 Phospholipase A1 (PLA1) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA1 enzymes. Where their function is known, PLA1s have been shown to act as digestive enzymes, possess central roles in ...
Richmond, Gregory S., Smith, Terry K.
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, 2019 Phospholipase C (PLC) family members constitute a family of diverse enzymes. Thirteen different family members have been cloned. These family members have unique structures that mediate various functions. Although PLC family members all appear to signal through the bi-products of cleaving phospholipids, it is clear that each family member, and at times
Colin A, Bill, Charlotte M, Vines
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PTEN regulates phospholipase D and phospholipase C [PDF]
Human Molecular Genetics, 2007 PTEN is an ubiquitously expressed tumor suppressor which plays a prominent role in the pathogenesis of many types of sporadic solid tumors, including breast cancer, as well as hematologic malignancies. Germline PTEN mutations cause 85% of Cowden syndrome (CS), characterized by a high risk of breast and thyroid cancers, and 65% of Bannayan-Riley ...
Christopher A, Alvarez-Breckenridge +2 more
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