Results 1 to 10 of about 144,128 (376)

The PNPLA family of enzymes: characterisation and biological role

Arhiv za Higijenu Rada i Toksikologiju, 2023
This paper brings a brief review of the human patatin-like phospholipase domain-containing protein (PNPLA) family. Even though it consists of only nine members, their physiological roles and mechanisms of their catalytic activity are not fully understood.
Lulić Ana-Marija, Katalinić Maja
doaj   +1 more source

Phospholipases C and D and Their Role in Biotic and Abiotic Stresses

Plants, 2021
Plants, as sessile organisms, have adapted a fine sensing system to monitor environmental changes, therefore allowing the regulation of their responses. As the interaction between plants and environmental changes begins at the surface, these changes are ...
Víctor M. González-Mendoza, M. E. Sánchez-Sandoval, Lizbeth A. Castro-Concha, S. M. Teresa Hernández-Sotomayor   +3 more
doaj   +1 more source

Functional Modulation of Human Macrophages by Secreted Phospholipases A₂: Implications in Cancer

Biomedicines, 2022
Cancer-related inflammation has recently emerged as an important component of cancer pathogenesis that is able to promote tumor initiation and progression, and the acquisition of the known hallmark capabilities, including evasion from immunosurveillance.
Maria Rosaria Galdiero, Ilaria Mormile, Francescopaolo Granata, Stefania Loffredo, Aikaterini Detoraki, Francesca Della Casa, Maria Luisa Trocchia, Annagioia Ventrici, Amato de Paulis, Francesca Wanda Rossi   +9 more
doaj   +1 more source

Forty Years of the Description of Brown Spider Venom Phospholipases-D

Toxins, 2020
Spiders of the genus Loxosceles, popularly known as Brown spiders, are considered a serious public health issue, especially in regions of hot or temperate climates, such as parts of North and South America.
L. H. Gremski, H. C. da Justa, Thaís Pereira da Silva, N. Polli, B. Antunes, J. Minozzo, A. C. M. Wille, A. Senff-Ribeiro, R. Arni, S. S. Veiga   +9 more
semanticscholar   +1 more source

Phospholipases A and Lysophospholipases in protozoan parasites

Microbial Cell, 2023
Phospholipases (PLs) and Lysophospholipases (LysoPLs) are a diverse group of esterases responsible for phospholipid or lysophospholipid hydrolysis. They are involved in several biological processes, including lipid catabolism, modulation of the immune ...
Perrine Hervé, Sarah Monic, Frédéric Bringaud, Loïc Rivière   +3 more
doaj   +1 more source

Anti-Candida Activity of Geraniol: Effect on Hydrolytic Enzyme Secretion and Biofilm Formation

Journal of Pure and Applied Microbiology, 2018
Existing antifungal drugs available today are low in efficacy, high in toxicity and cause multidrug resistance. Anti-Candida potential of geraniol, an acyclic monoterpene alcohol was evaluated and secretion of hydrolytic enzymes, adherence and biofilm ...
Yamini Sharma, Sumit Kumar Rastogi, Sahar Saadallah Amin Saadallah, Khadija Al Fadel, Nikhat Manzoor   +4 more
doaj   +1 more source

In silico analysis of cross reactivity among phospholipases from Hymenoptera species [version 2; peer review: 2 approved]

F1000Research, 2021
Background: Phospholipases are enzymes with the capacity to hydrolyze membrane lipids and have been characterized in several allergenic sources, such as hymenoptera species.
Yuliana Emiliani, Andrés Sánchez, Marlon Munera, Jorge Sánchez, Dilia Aparicio   +4 more
doaj   +1 more source

Substrate-Specific Inhibition Constants for Phospholipase A2 Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics. [PDF]

, 2019
Assaying lipolytic enzymes is extremely challenging because they act on water-insoluble lipid substrates, which are normally components of micelles, vesicles, and cellular membranes.
Armando, Aaron, Dennis, Edward A, Mouchlis, Varnavas D   +2 more
core   +6 more sources

Phospholipase gene expression during Paracoccidioides brasiliensis morphological transition and infection

Memorias do Instituto Oswaldo Cruz, 2013
Phospholipase is an important virulence factor for pathogenic fungi. In this study, we demonstrate the following: (i) the Paracoccidioides brasiliensis pld gene is preferentially expressed in mycelium cells, (ii) the plb1 gene is mostly up-regulated by ...
Deyze Alencar Soares, Marilia Barros Oliveira, Adriane Feijo Evangelista, Emerson Jose Venancio, Rosangela Vieira Andrade, Maria Sueli Soares Felipe, Silvana Petrofeza   +6 more
doaj   +1 more source

An amphitropic cAMP-binding protein in yeast mitochondria [PDF]

, 1989
: We describe the first example of a mitochondrial protein with a covalently attached phos-phatidylinositol moiety acting as a membrane anchor. The protein can be metabolically labeled with both stearic acid and inositol.
Bandlow W., Baranska J., Blok M., Brugge J., Burn P., Burn P., Cascales S. C., Cobon G. S., Cobon G. S., Cornell R., Courtneidge S. A., Cross G. A. M., Dils R. R., Dygas A., Gillfillan A. M., Guarnieri M., Hixson C. S., Hostetler K. Y., Jelsema C. L., Kraft A. S., Lassing I., Lassing I., Low M. G., Megli F. M., Meyer R. K., Muller G., Muller G., Muller G., Muller G., Nishizuka Y., Pelech S. L., Radika R., Rodel G., Rotman A., Schmidt M. F. G., Sefton B. M., Sleight R., Terce F., Towbin H., Wirtz K. W. A., Wirtz K. W. A., Wojtczak L., Yaffe M., Zborowski J.   +43 more
core   +3 more sources