Results 21 to 30 of about 43,115 (285)
Pancreatic phospholipase A2 activity in acute pancreatitis: A prognostic marker for early identification of patients at risk [PDF]
, 2002 Remarkably elevated levels of phospholipase A(2) (PLA(2)) are measurable in human blood samples in cases of acute pancreatitis. The source of the enzyme was first thought to be exclusively the pancreas, but now it is generally accepted that two ...
Aufenanger, Johannes +5 more
core +1 more source
Signal-activated phospholipase regulation of leukocyte chemotaxis
Journal of Lipid Research, 2009 Signal-activated phospholipases are a recent focus of the rapidly growing field of lipid signaling. The extent of their impact on the pathways regulating diverse cell functions is beginning to be appreciated.
Martha K. Cathcart
doaj +1 more source
Frontiers in Pharmacology, 2022 Nephrosclerosis patients have a high cardiovascular (CV) risk that is very often of more concern than the renal disease itself. We aimed to determine whether variants in phospholipase-related genes, associated with atherosclerosis and CV outcomes in the ...
Luz M. González +10 more
doaj +1 more source
Nuclear Inositides and Inositide-Dependent Signaling Pathways in Myelodysplastic Syndromes
Cells, 2020 Myelodysplastic syndromes (MDS) are a heterogeneous group of hematological malignancies characterized by peripheral blood cytopenia and abnormal myeloproliferation, as well as a variable risk of evolution into acute myeloid leukemia (AML). The nucleus is
Jie Xian +12 more
doaj +1 more source
Toxins, 2021 Nowadays, spider venom research focuses on the neurotoxic activity of small peptides. In this study, we investigated high-molecular-mass compounds that have either enzymatic activity or housekeeping functions present in either the venom gland or venom of
Sebastian Estrada-Gómez +4 more
doaj +1 more source
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. [PDF]
, 1994 Intracellular pathways leading from membrane receptor engagement to apoptotic cell death are still poorly characterized. We investigated the intracellular signaling generated after cross-linking of CD95 (Fas/Apo-1 antigen), a broadly expressed cell ...
Azuma, M +7 more
core +2 more sources
Journal of Fungi, 2019 Neutrophils activated with pathogens or their products induce formation of extracellular traps (NETs), but if this constitutes a general response against all pathogenic species in a single genus or intrageneric differences exist remains unknown, yet this
Lizbeth Campos-Garcia +5 more
doaj +1 more source
Toxins, 2020 A critical hurdle in ant venom proteomic investigations is the lack of databases to comprehensively and specifically identify the sequence and function of venom proteins and peptides.
Samira R. Aili +13 more
doaj +1 more source
Cyclosporin A inhibits PGE2 release from vascular smooth muscle cells [PDF]
, 1987 The influence of the fungoid undecapeptide cyclosporin A (CyA) on PGE2 release from cultured rat aortic smooth muscle cells was investigated in this study.
Koch, K. M. +3 more
core +1 more source
Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction [PDF]
, 2015 Botulinum neurotoxins (BoNTs) and some animal neurotoxins (-Bungarotoxin, -Btx, from elapid snakes and -Latrotoxin, -Ltx, from black widow spiders) are pre-synaptic neurotoxins that paralyse motor axon terminals with similar clinical outcomes in patients.
Duregotti, Elisa +6 more
core +4 more sources