Results 131 to 140 of about 72,860 (341)

Animal Experimentation: The Biological Significance of Phospholipase C β1 Gene Mutation in Mouse Sperm in the Acrosome Reaction, Fertilization, and Embryo Development [PDF]

, 2001
DooSeok Choi, Eunyoung Lee, Seongsoo Hwang, Kisun Jun, Dae‐Soo Kim, Byung-Koo Yoon, Hee‐Sup Shin, Je–Ho Lee   +7 more
openalex   +1 more source

A phospholipase linkAGE to SARS susceptibility [PDF]

Journal of Experimental Medicine, 2015
![Figure][1] Insight from John Schoggins During the aging process, immune functions decline, rendering the host more vulnerable to certain viruses. The mechanisms underlying this age-dependent susceptibility to infection are an active area of research.
openaire   +2 more sources

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins[S]

Journal of Lipid Research, 2010
Exosomes are bioactive vesicles released from multivesicular bodies (MVB) by intact cells and participate in intercellular signaling. We investigated the presence of lipid-related proteins and bioactive lipids in RBL-2H3 exosomes.
Caroline Subra, David Grand, Karine Laulagnier, Alexandre Stella, Gérard Lambeau, Michael Paillasse, Philippe De Medina, Bernard Monsarrat, Bertrand Perret, Sandrine Silvente-Poirot, Marc Poirot, Michel Record   +11 more
doaj   +1 more source

Lipoprotein-associated phospholipase A2 and carotid intima-media thickness in primary Sjögren syndrome

, 2021
Selcan Gültuna, Sevinç Can Sandıkçı, Hatice Kaplanoğlu, Fevzi Nuri Aydın, Funda Seher Özalp Ateş   +4 more
openalex   +2 more sources

Phospholipase A₂Activates Hemostasis

Drug Target Insights, 2007
Phospholipases A(2) (PLA(2)) are aggressive enzymes that can destroy phospholipids of cell membranes. The resulting cell fragments trigger the kallikrein-mediated contact phase of coagulation. The aim of the present study was to expose citrated whole blood to PLA(2) and to quantify thrombin generation in recalcified plasma.Normal citrated blood was ...
openaire   +4 more sources

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

Advanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen, Yahui Gao, Yulin Wang, Ting Lei, Zheng Qu, Yuhan An, Jiaxu Fu, Xin Li, Fangjun Liu, Yan Li   +9 more
wiley   +1 more source

CD36 Protein Is Involved in Store-operated Calcium Flux, Phospholipase A2 Activation, and Production of Prostaglandin E2 [PDF]

, 2011
Ondřej Kuda, Christopher M. Jenkins, James R. Skinner, Sung Ho Moon, Xiong Su, Richard W. Gross, Nada A. Abumrad   +6 more
openalex   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Complement-induced phospholipase A2 activation in experimental membranous nephropathy1 See Editorial by Shankland, p. 1204. [PDF]

, 2000
Andrey V. Cybulsky, Tomoko Takano, Joan Papillon, Alison J. McTavish   +3 more
openalex   +1 more source