Multidimensional toxicity of snake venom causes multi-organ damage and treatment challenges: a narrative review. [PDF]
Tong D, Chen L, Xu J.
europepmc +1 more source
Polyesterase activity and thermostability of carboxylesterases from Thermoleophilum album YS‐3
Three novel α/β‐hydrolases from thermophilic bacterium Thermoleophilum album display carboxylesterase and polyesterase activity. These enzymes hydrolyse PET, PLA and PCL both at high and moderate temperatures. TA21 shows superior activity, efficiently converting MHET to terephthalic acid. Structural features underlying substrate binding highlight their
Tatyana N. Chernikova +6 more
wiley +1 more source
Mucosal immune response modulated by secreted and membrane-bound hydrolases of <i>Candida albicans</i> in vulvovaginal candidiasis. [PDF]
Qian G, Ding L, Tan C, Wang L, Long C.
europepmc +1 more source
The emerging role of the Hippo signaling pathway in interorgan crosstalk
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song +2 more
wiley +1 more source
<i>Megalomyrmex milenae</i> Transcriptome Reveals a Complex Venom Cocktail. [PDF]
Sozanski KS +4 more
europepmc +1 more source
Bakuchiol: From structural mimicry to systems‐level skin biology
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley +1 more source
Investigating the presence of phospholipase and secreted aspartyle proteinase gene family in different genotypes of Candida albicans species. [PDF]
Mahmoodi M +6 more
europepmc +1 more source
ABSTRACT Aim The aim was to characterize the taxonomic and functional composition of the microbiome involved in primary endodontic infections and to evaluate their association with the periapical lesion size using shotgun metagenomic sequencing. Methodology Samples from primary root canal infections diagnosed with apical periodontitis were analysed ...
Virginia Pérez‐Carrasco +5 more
wiley +1 more source
Transcriptomic and Proteomic Study on Animal Venom: Looking Forward. [PDF]
Ho PL.
europepmc +1 more source
The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli +3 more
wiley +1 more source

