British Journal of Pharmacology, EarlyView.The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan +3 more
wiley +1 more source
Homology Analysis of <i>Polistes dominula</i> and <i>Vespula</i> spp. Venoms: A Comparative In Vitro and In Silico Study. [PDF]
Toxins (Basel)Morales M +4 more
europepmc +1 more source
Snake Venom PLA<sub>2</sub> as Anticoagulant Agents: Role of Crotoxin, from <i>Crotalus durissus</i> Rattlesnake, in Hemostasis. [PDF]
Toxins (Basel)Brasileiro-Martins LM +11 more
europepmc +1 more source
Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib +3 more
wiley +1 more source
New Insights into the Bioenergetic and Immunomodulatory Properties of Phospholipases A<sub>2</sub> from <i>Bothrops diporus</i> Venom. [PDF]
Toxins (Basel)Sasovsky DJ +8 more
europepmc +1 more source
Updates on intra‐articular corticosteroid administration in horses
Equine Veterinary Education, EarlyView.Summary Intra‐articular (IA) corticosteroid administration in equine athletes has gained increased attention recently, particularly in racing. Despite widespread corticosteroid use in equine practice for decades, there are still a lack of equine‐specific studies to address key questions related to their use.
K. Tanner +5 more
wiley +1 more source
Draft Genome Sequence of Multidrug-Resistant <i>Acinetobacter baumannii</i> smu isolated from a Bloodstream Infection in Sikkim, India. [PDF]
J GenomicsSharma R +4 more
europepmc +1 more source
Phospholipase C and phosphatidylinositol phospholipase C.
Clinical Chemistry, 1987 K, Hawrylak, R A, Stinson
openaire +2 more sources
The FEBS Journal, EarlyView.Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump +10 more
wiley +1 more source
The FEBS Journal, EarlyView.Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo +4 more
wiley +1 more source