Results 151 to 160 of about 22,290,738 (402)

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Lipoprotein-Associated Phospholipase A ₂ Protein Expression in the Natural Progression of Human Coronary Atherosclerosis [PDF]

, 2006
Frank D. Kolodgie, Allen Burke, Kristi Skorija, Elena Ladich, Robert Kutys, Addisalem Taye Makuria, Renu Virmani   +6 more
openalex   +1 more source

ATPase Effects on pro-Nutrients-mTOR Release LongFatty Acids Chains Which Under Mitochondrial Phospholipase, Synthase, & Synthetase Effects form Three ROR-alpha, beta, gamma Isoforms [PDF]

, 2021
Ashraf Marzouk, El Tantawi, Trisha Grevengoed, Eric Klett, Rosalind Coleman, J Rennison, T Mcelfresh, I Okere, H Patel, A Foster, Abo Alrob, O Lopaschuk, G, Russell A Debose Boyd, T Matt, Bianchi, Rongtao Zhu, Zhibing Ou, Xiongzhong Ruan, Jianping Gong, Qi Shen, Yuchen Bai, C N Ken, Yongjun Chang, Thomas Wang, Burris, Jalil Antoine, Bourgeois Thibaut, Mngaut Louise, Lagrost Laurent, Thomas Charles, A Thomas, Lagace, Allegretti Chiara, Denuccio Francesca, Rossato Letizia, D' Arrigo Paola, Gabriela Andrejeva, Sharon Gowan, Gigin Lin, Anne Christine, L Wong, Elham Shamsaei, N Yamashita, T Kawagishi, T Miyashita, T Nagatsuka, Sugiura, R Li, A Maminishkis, T Banzon, Q Wan, S Jalickee, R Rong, J Ahn, P Chen, P Suh, K Ye, Christine Crumbley, Yongjun Wang, Subhashis Banerjee, Thomas Burris, Yan Wang, Jernej Godec, Khadija Ben-Aissa, Kairong Cui, Keji Zhao, Shujiong Feng, Song Xu, Zhenzhen Wen, Yongliang Zhu, Ftima Cames, Markus Islinger, Sofia Guimares, Sreedhar Kilaru, Martin Schuster, Ashraf Marzouk, El Tantawi, Jay Stanley R Terlecky, Paul Koepke, Walton, Ftima Cames, Markus Islinger, Sofia Guimares, Sreedhar Kilaru, Martin Schuster, Jessica Paul A Watkins, Ellis, Barbara Lisowska, Dariusz Kosson, Karolina Domaracka, V Ramgolam, Y Sha, Jin Zhang, X Markovic-Plese, S, Jon Evasovic, Cherie Singer, Maria Daniel A Giles, Traci Moreno-Fernandez   +99 more
openalex   +1 more source

Plasma Proteomics Identifies Thousand‐and‐One–Amino Acid Kinase 3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

Arthritis &Rheumatology, EarlyView.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao   +15 more
wiley   +1 more source

Regulation of Cytosolic Phospholipase A2 Phosphorylation by Proteolytic Cleavage of Annexin A1 in Activated Mast Cells [PDF]

, 2012
Joon Hyun Kwon, Jea Hwang Lee, Ki Soon Kim, Youn Wook Chung, Ick Young Kim   +4 more
openalex   +1 more source

A multifaceted interplay between hemophagocytosis, IL‐18 and type I IFN distinguishes Still disease from other autoinflammatory diseases

Arthritis &Rheumatology, Accepted Article.
Objectives The unknown pathophysiology and the lack of specific features for systemic Juvenile Idiopathic arthritis and adult‐onset Still disease (collectively Still disease/SD) delays diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory diseases ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G.B. Grashof, Laurie Vaillant, Renske J.H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, ImmunAID consortium, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +17 more
wiley   +1 more source

The Role of Microbiota Metabolites Propionic Acid, p‐Cresol, and 4‐Ethylphenyl Sulfate in Autism Susceptibility: A Systematic Review

Autism Research, EarlyView.
ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis.
Laura Sandoni, Lisa Asta, Nicole Giompaolo, Rinvil Renaldi, Alberto Amaretti, Maddalena Rossi, Antonio M. Persico   +6 more
wiley   +1 more source

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

British Journal of Clinical Pharmacology, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath, Nicole S. L. Chan, Paul Joyce   +2 more
wiley   +1 more source

Etomoxir-carnitine, a novel pharmaco-metabolite of etomoxir, inhibits phospholipases A2 and mitochondrial respiration

Journal of Lipid Research
Mitochondrial fatty acid oxidation serves as an essential process for cellular survival, differentiation, proliferation, and energy metabolism. Numerous studies have utilized etomoxir (ETO) for the irreversible inhibition of carnitine palmitoylcarnitine ...
Sung Ho Moon, Xinping Liu, Christopher M. Jenkins, Beverly Gibson Dilthey, Gary J. Patti, Richard W. Gross   +5 more
doaj   +1 more source

Conservation and microdiversity of the phospholipase A (pldA) gene ofHelicobacter pyloriinfecting dyspeptics from different countries [PDF]

, 2001
Jacqueline Xerry, Robert J. Owen
openalex   +1 more source