Results 11 to 20 of about 72,860 (341)
Secretory Phospholipases A2 in Plants [PDF]
, 2019 Secreted phospholipases (sPLA2s) in plants are a growing group of enzymes that catalyze the hydrolysis of sn-2 glycerophospholipids to lysophospholipids and free fatty acids. Until today, around only 20 sPLA2s were reported from plants.
Fidelio, Gerardo Daniel +1 more
core +3 more sources
Search for and functional annotation of multi-domain PLA2 family proteins in flatworms
Вавиловский журнал генетики и селекцииThe phospholipase A2 (PLA2) is a superfamily of hydrolases that catalyze the hydrolysis of phospholipids and play a key role in many molecular processes in the cells and the organism as a whole.
M. E. Bocharnikova +2 more
doaj +2 more sources
Molecular effects of clinically relevant chemotherapeutic agents on choline phospholipid metabolism in triple negative breast cancer cells [PDF]
Translational OncologyTriple-negative breast cancer (TNBC) is the most lethal breast cancer subtype, leading to poor patient outcomes despite aggressive treatment with surgery, radiation, and chemotherapy. There are currently no clinical tests available which measure early on
Caitlin M. Tressler +5 more
doaj +2 more sources
Polarization of macrophages toward M2 phenotype is favored by reduction in iPLA2β (group VIA phospholipase A2)* [PDF]
, 2016 Macrophages are important in innate and adaptive immunity. Macrophage participation in inflammation or tissue repair is directed by various extracellular signals and mediated by multiple intracellular pathways.
Ashley, Jason W +7 more
core +4 more sources
F1000Research, 2021 Background: Phospholipases are enzymes with the capacity to hydrolyze membrane lipids and have been characterized in several allergenic sources, such as hymenoptera species.
Yuliana Emiliani +4 more
doaj +1 more source
Phospholipases in Gliomas: Current Knowledge and Future Perspectives from Bench to Bedside
Biomolecules, 2023 Phospholipases are essential intermediaries that work as hydrolyzing enzymes of phospholipids (PLs), which represent the most abundant species contributing to the biological membranes of nervous cells of the healthy human brain.
Maria Vittoria Marvi +15 more
doaj +1 more source
Phospholipases A and Lysophospholipases in protozoan parasites
Microbial Cell, 2023 Phospholipases (PLs) and Lysophospholipases (LysoPLs) are a diverse group of esterases responsible for phospholipid or lysophospholipid hydrolysis. They are involved in several biological processes, including lipid catabolism, modulation of the immune ...
Perrine Hervé +3 more
doaj +1 more source
International Journal of Molecular Sciences, 2011 Phospholipase A1 (PLA1) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA1 enzymes. Where their function is known, PLA1s have been shown to act as digestive enzymes, possess central roles in ...
Richmond, Gregory S., Smith, Terry K.
openaire +2 more sources
Phospholipases A in Trypanosomatids [PDF]
Enzyme Research, 2011 Phospholipases are a complex and important group of enzymes widespread in nature, that play crucial roles in diverse biochemical processes and are classified as A1, A2, C, and D. Phospholipases A1and A2activities have been linked to pathogenesis in various microorganisms, and particularly in pathogenic protozoa they have been implicated in cell ...
María Laura Belaunzarán +2 more
openaire +3 more sources
Human phospholipases A2: a functional and evolutionary analysis
Вавиловский журнал генетики и селекции, 2023 Phospholipases A2 (PLA2) are capable of hydrolyzing the sn-2 position of glycerophospholipids to release fatty acids and lysophospholipids. The PLA2 superfamily enzymes are widespread and present in most mammalian cells and tissues, regulating metabolism,
I. I. Turnaev +2 more
doaj +1 more source