Results 171 to 180 of about 31,410 (300)

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Insights into the antiviral activity of phospholipases A₂ (PLA₂s) from snake venoms. [PDF]

Int J Biol Macromol, 2020
Teixeira SC, Borges BC, Oliveira VQ, Carregosa LS, Bastos LA, Santos IA, Jardim ACG, Melo FF, Freitas LM, Rodrigues VM, Lopes DS.   +10 more
europepmc   +1 more source

Isolation of anticoagulant proteins from cobra venom (Naja nigricollis). Identity with phospholipases A2.

, 1980
Herbert J. Evans, Richard Franson, G. D. Qureshi, Winston F. Moo-Penn   +3 more
openalex   +1 more source

A Case of Recurrence of Severe Depressive Disorder With Flu—Neuroinflammatory Basis of Depressive Disorder

Progress in Neurology and Psychiatry, Volume 30, Issue 1, February 2026.
ABSTRACT This case highlights a relapse of major depressive disorder in an elderly man following a flu‐like illness, with clinical features and laboratory findings supporting a possible inflammatory contribution. It emphasises the relevance of the inflammatory theory of depression, especially in individuals with late‐life depression and recent immune ...
Nauman Malik, Mohamed A. Mohamed
wiley   +1 more source

Phospholipase A2 [PDF]

, 2020
openaire   +1 more source

The many dimeric faces of Lys49 PLA2‐like proteins: Conformational plasticity and membrane binding drive functional dimer states

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Lys49 secreted phospholipase A2‐like proteins (sPLA2s) are major myotoxins in viperid snake venoms, causing rapid muscle damage in envenomation. Beyond their clinical relevance, these small non‐catalytic proteins provide a model to study how quaternary structure and conformational dynamics enable catalysis‐independent membrane disruption ...
Diane C. A. Lima, Vinicius Firmino dos Santos, Bernardo Rassi, Richard J. Ward, Thereza A. Soares   +4 more
wiley   +1 more source

Inhibition of secreted phospholipases A2 by 2-oxoamides based on α-amino acids: Synthesis, in vitro evaluation and molecular docking calculations

, 2010
Varnavas D. Mouchlis, Victoria Magrioti, Efrosini Barbayianni, Nathan Cermak, Rob Oslund, Thomas Mavromoustakos, Michael H. Gelb, George Kokotos   +7 more
openalex   +1 more source

Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D [PDF]

, 2004
Yongxin Sun, Kazuhito Tsuboi, Yasuo Okamoto, Takeharu Tonai, Makoto Murakami, Ichiro Kudo, Natsuo Ueda   +6 more
openalex   +1 more source

Heart matters: How glucose‐ and lipid‐modulating drugs remodel epicardial adipose tissue accumulation, inflammatory patterns and browning

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 878-894, February 2026.
Abstract Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot located between the myocardium and the visceral pericardium, exerting direct paracrine and vasocrine effects on the heart and coronary vessels. Under physiological conditions, EAT supports myocardial energy metabolism and thermoregulation through fatty acid supply and
Elisabeth Heuboeck, Charnkamal Singh Bhogal, Markus Mandl   +2 more
wiley   +1 more source

Two lipid-anchored cAMP-binding proteins in the yeast Saccharomyces cerevisiae are unrelated to the R subunit of cytoplasmic protein kinase A [PDF]

, 1991
Bandlow, Wolfhard, Müller, Günter
core   +1 more source