Results 221 to 230 of about 31,410 (300)

The Inhibitory Effects of Zinc Oxide Nanoparticles on Clinical Isolates of Malassezia in Dogs

open access: yesVeterinary Medicine and Science, Volume 12, Issue 1, January 2026.
Zinc oxide nanoparticles inhibit the growth and virulence of Malassezia pachydermatis clinical isolates from dogs. ZnO NPs exhibit potent fungicidal activity at low concentrations (MIC 3.90–7.81 ppm) and significantly downregulate the expression of Phospholipase A2 and Aspartyl proteinase genes, key virulence factors. This demonstrates the potential of
Alaleh Vazifehdust   +5 more
wiley   +1 more source

Comparison of Predatory Phenotypes and Genotypes Between Bdellovibrio sp. BIS2 and Bacteriovorax sp. HI3 Isolated From the Same Freshwater Environment

open access: yesEnvironmental Microbiology, Volume 28, Issue 1, January 2026.
Bdellovibrio and like organisms (BALOs) have gained attraction owing to their ecological and practical significance. This study comparatively investigated two BALO strains from the same freshwater pond, Bdellovibrio sp. BIS2 and Bacteriovorax sp. HI3, and revealed significant variation in their predatory behaviours and associated genetic profiles ...
Tomomi Sugiyama   +6 more
wiley   +1 more source

Anti-platelet aggregation activity of two novel acidic Asp49-phospholipases A2 from Bothrops brazili snake venom

open access: green, 2017
Juliana C. Sobrinho   +14 more
openalex   +2 more sources

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

open access: yesBrain Pathology, Volume 36, Issue 1, January 2026.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li   +7 more
wiley   +1 more source

Tumor‐Derived Prostaglandin E2 Promotes Colorectal Cancer Progression by Inducing N2‐Type TAN Polarization

open access: yesCancer Science, Volume 117, Issue 1, Page 19-32, January 2026.
We demonstrated that PGE2 released from LDs in CRC cells plays important roles in N2‐type TANs polarization. PGE2 enters neutrophils through its receptor EP2/EP4 to stimulate ROS‐mediated FOXO3a methylation, thereby increasing the polarization of N2‐type TANs.
Yue Han   +3 more
wiley   +1 more source

Comprehensive Colorectal Cancer Stem Cell Transcriptomic Signatures That Can Predict Patient Prognostic Outcomes

open access: yesCancer Science, Volume 117, Issue 1, Page 130-144, January 2026.
We characterized colorectal cancer stem‐like cell (CRC‐SC)–derived transcriptomic subtypes based on mRNA expression of 57 patient‐derived SC lines. Expression profiles were compared with normal colonic epithelium stem‐like cells (NCE‐SCs), yielding differentially expressed genes.
Fumihiko Kakizaki   +13 more
wiley   +1 more source

Myeloid-specific deletion of group VIA calcium-independent phospholipase A2 induces pro-inflammatory LPS response predominantly in male mice via MIP-1α activation

open access: hybrid
Lukas Klement   +8 more
openalex   +1 more source

Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms

open access: yesCell Proliferation, Volume 59, Issue 1, January 2026.
Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng   +4 more
wiley   +1 more source

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