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The Phospholipid Research Center: Current Research in Phospholipids and Their Use in Drug Delivery
Pharmaceutics, 2020 This review summarizes the research on phospholipids and their use for drug delivery related to the Phospholipid Research Center Heidelberg (PRC). The focus is on projects that have been approved by the PRC since 2017 and are currently still ongoing or ...
Simon Drescher, Peter van Hoogevest
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Host Fatty Acid Utilization by
mBio, 2020 Staphylococcus aureus utilizes the fatty acid (FA) kinase system to activate exogenous FAs for membrane synthesis. We developed a lipidomics workflow to determine the membrane phosphatidylglycerol (PG) molecular species synthesized by S.
Matthew W. Frank +6 more
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Journal of Lipid Research, 1966 Macrophages obtained from the peritoneal cavity of rabbits were incubated with phosphate-32P in order to investigate the synthesis of phospholipid by these cells.
A.J. Day, N.H. Fidge, G.N. Wilkinson
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Transcriptional regulation in bacterial membrane lipid synthesis
Journal of Lipid Research, 2009 This review covers the main transcriptional mechanisms that control membrane phospholipid synthesis in bacteria. The fatty acid components are the most energetically expensive modules to produce; thus, the regulation of fatty acid production is very ...
Yong-Mei Zhang, Charles O. Rock
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Effect of light on extraction of lipid from retinal rods
Journal of Lipid Research, 1967 Chloroform-methanol 2:1 removes a significantly greater quantity of lipid from bleached bovine retinal rods than from a dark-adapted counterpart. The extracts contain phosphatidyl serine, phosphatidyl choline, phosphatidyl ethanolamine, sphingomyelin ...
Ralph G. Adams
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Biomolecules, 2021 Young-of-the-year (YOY) striped bass (Morone saxatilis) suffer significant mortality during their first winter. While causes of this mortality are unclear, lipids may play role in adapting to winter stresses, including thermal change and food scarcity ...
Kare A. Tonning +2 more
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An optimized negative-staining protocol of electron microscopy for apoE4•POPC lipoprotein
Journal of Lipid Research, 2010 Apolipoprotein E (apoE), one of the major protein components of lipoproteins in the peripheral and central nervous systems, regulates cholesterol metabolism through its interaction with members of the low density lipoprotein receptor family.
Lei Zhang +5 more
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Journal of Lipid Research, 2010 Acyl-CoA:glycerol-3-phosphate acyltransferase (GPAT) catalyzes the first step during de novo synthesis of glycerolipids. Mammals have at least four GPAT isoforms. Here we report the further characterization of the two recently identified microsomal GPAT3
Dandan Shan +7 more
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Journal of Lipid Research, 2008 Elucidation of the metabolic pathways of triacylglycerol (TAG) synthesis is critical to the understanding of chronic metabolic disorders such as obesity, cardiovascular disease, and diabetes.
Cynthia A. Nagle +6 more
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ADMET and DMPK, 2020 The bioavailability of tetracyclines is markedly decreased when co-administered with antacids, milk, or food containing Ca2+. Previously, it was suggested that the effective intestinal permeation of tetracycline (TC) was decreased due to Ca2+ linked ...
Sachika Yamauchi +2 more
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