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The Phospholipid Research Center: Current Research in Phospholipids and Their Use in Drug Delivery

open access: yesPharmaceutics, 2020
This review summarizes the research on phospholipids and their use for drug delivery related to the Phospholipid Research Center Heidelberg (PRC). The focus is on projects that have been approved by the PRC since 2017 and are currently still ongoing or ...
Simon Drescher, Peter van Hoogevest
doaj   +1 more source

Phospholipid synthesis inside phospholipid membrane vesicles

open access: yesCommunications Biology, 2022
AbstractConstruction of living artificial cells from genes and molecules can expand our understanding of life system and establish a new aspect of bioengineering. However, growth and division of cell membrane that are basis of cell proliferation are still difficult to reconstruct because a high-yielding phospholipid synthesis system has not been ...
Sumie Eto   +6 more
openaire   +3 more sources

Host Fatty Acid Utilization by Staphylococcus aureus at the Infection Site

open access: yesmBio, 2020
Staphylococcus aureus utilizes the fatty acid (FA) kinase system to activate exogenous FAs for membrane synthesis. We developed a lipidomics workflow to determine the membrane phosphatidylglycerol (PG) molecular species synthesized by S.
Matthew W. Frank   +6 more
doaj   +1 more source

A New Type of LSPR Sensor Featuring Immobilized Liposome or Phospholipid Single Layer

open access: yesProceedings, 2018
We have fabricated a new type of LSPR sensor featuring immobilized liposome or phospholipid single layer. LSPR principally shows an ultrahigh sensitivity on surface dielectric environmental change due to interaction with target, but little has been ...
Masahiro Kawasaki   +6 more
doaj   +1 more source

Effect of cholesterol in suspension on the incorporation of phosphate into phospholipid by macrophages in vitro

open access: yesJournal of Lipid Research, 1966
Macrophages obtained from the peritoneal cavity of rabbits were incubated with phosphate-32P in order to investigate the synthesis of phospholipid by these cells.
A.J. Day, N.H. Fidge, G.N. Wilkinson
doaj   +1 more source

Transcriptional regulation in bacterial membrane lipid synthesis

open access: yesJournal of Lipid Research, 2009
This review covers the main transcriptional mechanisms that control membrane phospholipid synthesis in bacteria. The fatty acid components are the most energetically expensive modules to produce; thus, the regulation of fatty acid production is very ...
Yong-Mei Zhang, Charles O. Rock
doaj   +1 more source

Effect of light on extraction of lipid from retinal rods

open access: yesJournal of Lipid Research, 1967
Chloroform-methanol 2:1 removes a significantly greater quantity of lipid from bleached bovine retinal rods than from a dark-adapted counterpart. The extracts contain phosphatidyl serine, phosphatidyl choline, phosphatidyl ethanolamine, sphingomyelin ...
Ralph G. Adams
doaj   +1 more source

Overwinter Changes in the Lipid Profile of Young-of-the-Year Striped Bass (Morone saxatilis) in Freshwater Ponds

open access: yesBiomolecules, 2021
Young-of-the-year (YOY) striped bass (Morone saxatilis) suffer significant mortality during their first winter. While causes of this mortality are unclear, lipids may play role in adapting to winter stresses, including thermal change and food scarcity ...
Kare A. Tonning   +2 more
doaj   +1 more source

An optimized negative-staining protocol of electron microscopy for apoE4•POPC lipoprotein

open access: yesJournal of Lipid Research, 2010
Apolipoprotein E (apoE), one of the major protein components of lipoproteins in the peripheral and central nervous systems, regulates cholesterol metabolism through its interaction with members of the low density lipoprotein receptor family.
Lei Zhang   +5 more
doaj   +1 more source

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