Results 31 to 40 of about 209,802 (322)

Phospholipid Scramblases [PDF]

open access: yesLipid Insights, 2015
The distribution of phospholipid types between the two leaflets of a membrane bilayer is a controlled feature of membrane structure. One of the two membrane catalytic activities governing this distribution randomizes the composition of the two leaflets–-the phospholipid scramblases.
openaire   +2 more sources

Thermodynamic Approach to Phase Coexistence in Ternary Phospholipi-Cholesterol Mixtures [PDF]

open access: yesPhysical Review Letters 106 (2011) 128104, 2011
We introduce a simple and predictive model for determining the phase stability of ternary phospholipid-cholesterol mixtures. Assuming that competition between the liquid and gel order of the phospholipids is the main driving force behind lipid segregation, we derive a Gibbs free-energy of mixing, based on the thermodynamic properties of the lipids main
arxiv   +1 more source

Interaction of Small Ionic Species With Phospholipid Membranes: The Role of Metal Coordination

open access: yesFrontiers in Materials, 2019
In studies of the transfer, distribution and biochemical activity of metal ions it is typically assumed that the phospholipid bilayer acts as an inert barrier.
Chanh Thi Minh Le   +4 more
doaj   +1 more source

Phospholipids as ionophores. [PDF]

open access: yesJournal of Biological Chemistry, 1976
The ionophoretic capabilities of phospholipids have been examined by direct measurement in a Pressman cell of the phospholipid-mediated translocation of cations across an organic phase separating two aqueous phases. Cardiolipin and phosphatidic acid were the most active inonophores among the phospholipids tested, with activities comparable to that of ...
C A Tyson, H Vande Zande, David E. Green
openaire   +2 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Decoupling of dipolar and hydrophobic motions in biological membranes [PDF]

open access: yesarXiv, 2020
Cells use homeostatic mechanisms to maintain an optimal composition of distinct types of phospholipids in cellular membranes. The hydrophilic dipolar layer at the membrane interface, composed of phospholipid headgroups, regulates the interactions between cell membranes and incoming molecules, nanoparticles, and viruses.
arxiv  

Laboratory X-ray Study of the Phospholipid Monolayers at the Water Surface [PDF]

open access: yesJETP Lett. 106, 534 (2017), 2017
The possibility of laboratory X-ray reflectometry study of the structure of dimyristoyl phosphatidylserine (DMPS) phospholipid monolayers on the water surface in various phase states has been demonstrated.
arxiv   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Using neurolipidomics to identify phospholipid mediators of synaptic (dys)function in Alzheimer’s Disease

open access: yesFrontiers in Physiology, 2013
Not all of the mysteries of life lie in our genetic code. Some can be found buried in our membranes. These shells of fat, sculpted in the central nervous system into the cellular (and subcellular) boundaries of neurons and glia, are themselves complex ...
Steffany A L Bennett   +11 more
doaj   +1 more source

Putting the 'P' into Phospholipids

open access: yesCHIMIA, 2011
Despite almost hundred years of dedicated research, the synthesis of phospholipids remains a challenge. Here, we briefly review important trends and point out possible future directions that might lead to interesting new probes for the membrane environment. An improved liposome purification and concentration protocol rounds up the article.
Fedotenko Illya A.   +4 more
openaire   +5 more sources

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