Results 41 to 50 of about 565,738 (381)

An amphitropic cAMP-binding protein in yeast mitochondria [PDF]

, 1989
: We describe the first example of a mitochondrial protein with a covalently attached phos-phatidylinositol moiety acting as a membrane anchor. The protein can be metabolically labeled with both stearic acid and inositol.
Bandlow W., Baranska J., Blok M., Brugge J., Burn P., Burn P., Cascales S. C., Cobon G. S., Cobon G. S., Cornell R., Courtneidge S. A., Cross G. A. M., Dils R. R., Dygas A., Gillfillan A. M., Guarnieri M., Hixson C. S., Hostetler K. Y., Jelsema C. L., Kraft A. S., Lassing I., Lassing I., Low M. G., Megli F. M., Meyer R. K., Muller G., Muller G., Muller G., Muller G., Nishizuka Y., Pelech S. L., Radika R., Rodel G., Rotman A., Schmidt M. F. G., Sefton B. M., Sleight R., Terce F., Towbin H., Wirtz K. W. A., Wirtz K. W. A., Wojtczak L., Yaffe M., Zborowski J.   +43 more
core   +6 more sources

Interaction of Small Ionic Species With Phospholipid Membranes: The Role of Metal Coordination

Frontiers in Materials, 2019
In studies of the transfer, distribution and biochemical activity of metal ions it is typically assumed that the phospholipid bilayer acts as an inert barrier.
Chanh Thi Minh Le, Aamd Houri, Nimalka Balage, Brian J. Smith, Adam Mechler   +4 more
doaj   +1 more source

Functional and Biogenetical Heterogeneity of the Inner Membrane of Rat-Liver Mitochondria [PDF]

, 1971
Rat liver mitochondria were fragmented by a combined technique of swelling, shrinking, and sonication. Fragments of inner membrane were separated by density gradient centrifugation.
Allmann D. W., Ashwell M., Beattie D. S., Beattie D. S., Brunner G., Burstone M. S., Davis K. A., Delbruck A., Fiske C. H., Folch J., Gear A. R. L., Gear A. R. L., Gear A. R. L., Gelder B. F., Gotterer G. S., Hasegawa E., Hawley E. S., Johnson A. B., Klingenberg M., Kuntzel H., Labbe R. F., Lentz P. E., Neupert W., Neupert W., Novikoff A. B., Ohnishi K., Omura T., Parsons D. F., Parsons D. F., Pette D., Pollak J. K., Pullmann M. E., Raw J., Raw J., Reith A., Schneider W. C., Schuel H., Schumacher H.-H., Sebald W., Sebald W., Seligman A. M., Sies H., Sottocasa G. L., Stoffel W., Strecker H. J., Swick R. W., Szarkowska L., Tabor C. W., Tol A., Vazquez J. J., Yonetani T.   +50 more
core   +1 more source

Targeting Phospholipid Metabolism in Cancer

Frontiers in Oncology, 2016
All cancers tested so far display abnormal choline and ethanolamine phospholipid metabolism, which has been detected with numerous magnetic resonance spectroscopy (MRS) approaches in cells, animal models of cancer, as well as the tumors of cancer ...
M. Cheng, Z. Bhujwalla, K. Glunde
semanticscholar   +1 more source

Phospholipids as ionophores. [PDF]

Journal of Biological Chemistry, 1976
The ionophoretic capabilities of phospholipids have been examined by direct measurement in a Pressman cell of the phospholipid-mediated translocation of cations across an organic phase separating two aqueous phases. Cardiolipin and phosphatidic acid were the most active inonophores among the phospholipids tested, with activities comparable to that of ...
C A Tyson, H Vande Zande, David E. Green
openaire   +2 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Conformational photoswitching of a synthetic peptide foldamer bound within a phospholipid bilayer [PDF]

, 2016
The dynamic properties of foldamers, synthetic molecules that mimic folded biomolecules, have mainly been explored in free solution.We report on the design, synthesis, and conformational behavior of photoresponsive foldamers bound in a phospholipid ...
Clayden, Jonathan, De Poli, Matteo, Lorch, Mark, Quinonero, Ophélie, Webb, Simon J., Zawodny, Wojciech   +5 more
core   +2 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Using neurolipidomics to identify phospholipid mediators of synaptic (dys)function in Alzheimer’s Disease

Frontiers in Physiology, 2013
Not all of the mysteries of life lie in our genetic code. Some can be found buried in our membranes. These shells of fat, sculpted in the central nervous system into the cellular (and subcellular) boundaries of neurons and glia, are themselves complex ...
Steffany A L Bennett, Steffany A L Bennett, Nicolas eValenzuela, Nicolas eValenzuela, Hongbin eXu, Hongbin eXu, Bettina eFranko, Bettina eFranko, Stephen eFai, Stephen eFai, Daniel eFigeys, Daniel eFigeys   +11 more
doaj   +1 more source

Coarse-Grained Models of Biological Membranes within the Single Chain Mean Field Theory

, 2010
The Single Chain Mean Field theory is used to simulate the equilibrium structure of phospholipid membranes at the molecular level. Three levels of coarse-graining of DMPC phospholipid surfactants are present: the detailed 44-beads double tails model, the
Al-Anber, Al-Anber, Altevogt, Ben-Shaul, Ben-Shaul, Cooke, Damodaran, Damodaran, Daoulas, Daoulas, Doi, Fraaije, Goetz, Heller, Hyvonen, Koynova, Kucerka, Lyubartsev, Mackie, Mae, Marcelja, Marcelja, Marrink, Mathai, Muller, Muller, Muller, Nagle, Robinson, Rosenbluth, Sergey Pogodin, Shelley, Shelley, Shvartzman-Cohen, Smondyrev, Soldera, Tieleman, Tuckerman, Venturolia, Vladimir A. Baulin   +39 more
core   +1 more source