Results 61 to 70 of about 565,738 (381)

Structural Changes Of Dha-Containing Phospholipids By K+ And Na+ Cations In Nerve Cell Membranes [PDF]

, 2010
Understanding the structure and dynamics of a docosa hexaenoic acid (DHA) containing phospholipid monomer within membranes is essential for recognizing the bilayer function in central nervous system. It has been recognized that the electrical impulses in
Khodayari, N., Mollaamin, F., Monajjemi, M.   +2 more
core  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues

Journal of Lipid Research, 2005
Lysosomal phospholipase A2 (LPLA2) is an acidic phospholipase that is highly expressed in alveolar macrophages and that may play a role in the catabolism of pulmonary surfactant.
Miki Hiraoka, Akira Abe, James A. Shayman   +2 more
doaj  

Structural properties and Raman spectroscopy of lipid Langmuir monolayers at the air-water interface

, 2010
Spectra of octadecylamine (ODA) Langmuir monolayers and egg phosphatidylcholine (PC)/ODA-mixed monolayers at the air-water interface have been acquired.
Aroca., Bohdana, Chamberlain, Chazalet, Curtis, Fendler, Frank, Greenhall, Guo, Hill, Hongxin Dang, Honig, Huang, Ignes-mullol, Kobayashi, Lee, Lin, Lin-Vien, Maquelin, Marg, Meldrum, Michota, Moskovits, Nie, Patil, Peter, Pettinger, Rivas, Roberts, Samned, Schoefisch, Shuxi Dai, Song, Spiker, Taylor, Thompson, Tollner, Tsen, Wong, Xingtang Zhang, Yabin Huang, Young, Zuliang Du   +42 more
core   +1 more source

Phospholipid fatty acid analysis to monitor the co-composting process of olive oil mill wastes and organic household refuse [PDF]

, 2008
The co-composting of olive oil mill wastes and household refuse was followed for 5 months. During the thermophilic phase of composting, the aerobic heterotrophic bacteria (AHB) count, showed a significant rise with a slight regression of fungal biomass ...
Amir, Soumia, Barje, Farid, Cegarra, Juan, Hafidi, Mohamed, Merlina, Georges, Pinelli, Eric, Revel, Jean-Claude, Winterton, Peter   +7 more
core   +4 more sources

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Kinetic dependence of phospholipase A2 activity on the detergent Triton X-100

Journal of Lipid Research, 1973
A kinetic analysis is presented for the dependence of one form of phospholipase A2 from cobra (Naja naja) venom on the presence of the nonionic detergent Triton X-100 for its activity towards egg phosphatidylcholine and synthetic dipalmitoyl ...
Edward A. Dennis
doaj  

Recent Advances in Intranasal Liposomes for Drug, Gene, and Vaccine Delivery

Pharmaceutics, 2023
Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles produced from cholesterol and phospholipids. Recently, liposomes have been widely administered intranasally for systemic and brain delivery. From the nasal cavity, liposome-
Van-An Duong, Thi-Thao-Linh Nguyen, Han-Joo Maeng   +2 more
doaj   +1 more source

Porphyrin–phospholipid liposomes permeabilized by near-infrared light

Nature Communications, 2014
The delivery of therapeutic compounds to target tissues is a central challenge in treating disease. Externally controlled drug release systems hold potential to selectively enhance localized delivery.
Kevin A. Carter, S. Shao, Matthew I. Hoopes, Dandan Luo, B. Ahsan, V. Grigoryants, Wentao Song, Haoyuan Huang, Guojian Zhang, R. Pandey, J. Geng, B. Pfeifer, C. Scholes, J. Ortega, M. Karttunen, J. Lovell   +15 more
semanticscholar   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source