Results 71 to 80 of about 14,880 (275)

Total synthesis of the endogenous inflammation resolving lipid resolvin D2 using a common lynchpin

open access: yesBeilstein Journal of Organic Chemistry, 2013
The total synthesis of the endogenous inflammation resolving eicosanoid resolvin D2 (1) is described. The key steps involved a Wittig reaction between aldehyde 5 and the ylide derived from phosphonium salt 6 to give enyne 17 and condensation of the same ...
John Li   +3 more
doaj   +1 more source

Poly(ionic liquid) semi-interpenetrating network multi-responsive hydrogels [PDF]

open access: yes, 2016
Herein we describe poly(ionic liquid) hydrogel actuators that are capable of responding to multiple stimuli, namely temperature, ionic strength and white light irradiation.
Burns, John   +4 more
core   +2 more sources

Sulfonium‐Based Antimicrobial Block Copolymers: Influence of Hydrophobicity on Biological Activity and Antibiotic Synergy

open access: yesMacromolecular Rapid Communications, EarlyView.
Sulfonium‐based antimicrobial block copolymers combine an active cationic hydrophobic block with a neutral hydrophilic block to improve cytocompatibility. The hydrophobicity of the sulfonium‐based block controls the activity against S. aureus and E coli.
Sidra Kanwal   +5 more
wiley   +1 more source

A Strategy for the Design of Flame Retardants: Cross-linking Processes [PDF]

open access: yes, 1989
Cross-linking is identified as an effective means for flame retardation of polymers and schemes for the cross-linking of poly(ethylene terephthalate) and poly(methyl methacrylate) are presented.
Sirdesai, Sunil J.   +2 more
core   +1 more source

Stereoselective syntheses of the antihistaminic drug olopatadine and its E-isomer [PDF]

open access: yes, 2017
Practical stereoselective synthetic routes to the antihistaminic drug olopatadine and its E-isomer have been developed, the key steps being a trans stereoselective Wittig olefination using a nonstabilized phosphorus ylide and a stereoselective Heck ...
Amat Tusón, Mercedes   +5 more
core   +1 more source

Cyanoacetamidobetaine—A Zwitterionic Nitrile Derivative

open access: yesChemistryOpen, EarlyView.
The reaction of sodium dicyanamide with betainium chloride in aqueous solution affords N‐cyano‐2‐(trimethylammonio)acetaminide (cyanoacetamidobetaine). Single crystal X‐ray diffraction reveals a monoclinic structure comprising a trimethylammonium head group connected to a cyanoacetaminide unit via a methylene bridge.
Pan Duan   +5 more
wiley   +1 more source

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

open access: yesJournal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá   +4 more
wiley   +1 more source

Azidophosphonium salt-directed chemoselective synthesis of (E)/(Z)-cinnamyl-1H-triazoles and regiospecific access to bromomethylcoumarins from Morita–Baylis–Hillman adducts

open access: yesBeilstein Journal of Organic Chemistry, 2020
The direct transformation of Morita–Baylis–Hillman (MBH) adducts into molecules of interest is a crucial process wherein allylic hydroxy-protected or halogenated MBH adducts are commonly preferred.
Soundararajan Karthikeyan   +4 more
doaj   +1 more source

Ionogel Actuators: A Review

open access: yesSmartBot, EarlyView.
Ionogels dynamically and functionally couple ionic liquids with polymer networks, enabling multiscale programmable deformation and motion under electrical, magnetic, optical, thermal, humidity, and chemical stimuli. This article systematically elucidates the constituent components, structural design, and multiscale actuation mechanisms of ionogel ...
Dezhou Cao   +5 more
wiley   +1 more source

Rapid Generation of Fusable Cell Beads for Multi‐Scale Human Living Materials Assembly

open access: yesSmall Methods, EarlyView.
Living beads are produced through the combination of metabolic glycoengineering, click chemistry, and superhydrophobic surfaces, to develop a spheroid alternative for bottom‐up tissue engineering and disease modeling. The living beads present a size independent of cell density and a rapid fabrication methodology, providing a platform that can fuse into
Beatriz S. Moura   +5 more
wiley   +1 more source

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