Results 1 to 10 of about 9,926 (149)
Protocol to assess substrate dephosphorylation by serine/threonine phosphoprotein phosphatases in vitro [PDF]
STAR Protocols, 2023 Summary: Serine/threonine protein phosphatase 2 (PP2A) forms heterotrimeric holoenzymes, where a scaffold subunit bridges the PP2A catalytic subunit to a B regulatory subunit, e.g., B55α.
Jason S. Wasserman +6 more
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Molecular evolution of phosphoprotein phosphatases in Drosophila. [PDF]
PLoS ONE, 2011 Phosphoprotein phosphatases (PPP), these ancient and important regulatory enzymes are present in all eukaryotic organisms. Based on the genome sequences of 12 Drosophila species we traced the evolution of the PPP catalytic subunits and noted a ...
Márton Miskei +4 more
doaj +2 more sources
BBA Advances, 2021 Background: Phosphoprotein phosphatases (PPP) belong to the PPP Sequence family, which in turn belongs to the broader metallophosphoesterase (MPE) superfamily.
David Kerk +5 more
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Life, 2021 Protein phosphorylation is one of the most widely observed and important post-translational modification (PTM) processes. Protein phosphorylation is regulated by protein kinases, each of which covalently attaches a phosphate group to an amino acid side ...
Seung-Hyeon Seok
doaj +1 more source
Protein Serine/Threonine Phosphatase Type 2C of Leishmania mexicana
Frontiers in Cellular and Infection Microbiology, 2021 Protein phosphorylation and dephosphorylation are increasingly recognized as important processes for regulating multiple physiological mechanisms.
Alma Reyna Escalona-Montaño +10 more
doaj +1 more source
Biomolecules, 2023 Sodium bicarbonate stress caused by NaHCO3 is one of the most severe abiotic stresses affecting agricultural production worldwide. However, little attention has been given to the molecular mechanisms underlying plant responses to sodium bicarbonate ...
Qiang Li +7 more
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Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification
Molecular Systems Biology, 2023 Phosphoprotein phosphatases (PPPs) regulate major signaling pathways, but the determinants of phosphatase specificity are poorly understood. This is because methods to investigate this at scale are lacking.
Jamin B Hein +10 more
doaj +1 more source
Nature Communications, 2020 The substrate specificity of phosphoprotein phosphatases PP1 and PP2A depends on their catalytic and regulatory subunits. Using proteomics approaches, the authors here provide insights into the sequence specificity of the catalytic subunits and their ...
Bernhard Hoermann +11 more
doaj +1 more source
Freshwater Cyanobacterial Toxins, Cyanopeptides and Neurodegenerative Diseases
Toxins, 2023 Cyanobacteria produce a wide range of structurally diverse cyanotoxins and bioactive cyanopeptides in freshwater, marine, and terrestrial ecosystems.
Galina Nugumanova +4 more
doaj +1 more source
Biomolecules, 2021 Isotopically dimethyl labeling was applied in a quantitative post-translational modification (PTM) proteomic study of phosphoproteomic changes in the drought responses of two contrasting soybean cultivars.
Atieh Moradi +12 more
doaj +1 more source