Results 21 to 30 of about 31,335 (237)

Simultaneous Adsorption of Intact Glycoproteins and Phosphoproteins Using Hydrophilic Titanium (IV) Ion-Immobilized Cotton Fiber Functionalized by Phytic Acid Assembly

Journal of Chemistry, 2023
Protein glycosylation and phosphorylation are two important post-translational modifications and play significant roles in various biological processes.
Dawei Zhang, Zhenhua Zhou, Guifeng Sun, Shiying Chen, Minzhi Jiang, Zihan Yao, Anthony Chukwunonso Ogbuehi, Hao Wang, Lei Jin   +8 more
doaj   +1 more source

Differential phosphoproteome regulation of nucleus accumbens in environmentally enriched and isolated rats in response to acute stress. [PDF]

PLoS ONE, 2013
Increasing evidence shows that stress contributes to the pathogenesis of major depressive disorder which is a severe neuropsychiatric disorder and influences over 10% of the world's population.
Xiuzhen Fan, Dingge Li, Yafang Zhang, Thomas A Green   +3 more
doaj   +1 more source

Salt-induced phosphoproteomic changes in the subfornical organ in rats with chronic kidney disease

Renal Failure, 2023
Objectives Subfornical organ (SFO) is vital in chronic kidney disease (CKD) progression caused by high salt levels. The current study investigated the effects of high salt on phosphoproteomic changes in SFO in CKD rats.Methods 5/6 nephrectomized rats ...
Xin Wang, Huizhen Wang, Jiawen Li, Lanying Li, Yifan Wang, Aiqing Li   +5 more
doaj   +1 more source

Effect of combined application of premixed bioceramic paste and diode laser in vital pulp therapy: an immunohistochemical randomized controlled split-mouth in vivo animal experiment [PDF]

Restorative Dentistry & Endodontics
Objectives This study aimed to evaluate the effect of premixed bioceramic paste (Well-Root PT; Vericom) compared to mineral trioxide aggregate (MTA) on the expression of the mineralization-related marker dentin sialoprotein (DSP) in dental pulp following
Mo’men A. Salama, Dalia M. Fayyad, Mohamed I. Rabie, Manar A. A. Selim, Mahmoud F. Ahmed   +4 more
doaj   +1 more source

In Situ Growth Intercalation Structure MXene@Anatase/Rutile TiO₂ Ternary Heterojunction with Excellent Phosphoprotein Detection in Sweat

Biosensors, 2022
Abnormal protein phosphorylation may relate to diseases such as Alzheimer’s, schizophrenia, and Parkinson’s. Therefore, the real-time detection of phosphoproteins in sweat was of great significance for the early knowledge, detection, and treatment of ...
Yuting Qiao, Xianrong Liu, Zhi Jia, Peng Zhang, Li Gao, Bingxin Liu, Lijuan Qiao, Lei Zhang   +7 more
doaj   +1 more source

Medicago PhosphoProtein Database: a repository for Medicago truncatula phosphoprotein data [PDF]

Frontiers in Plant Science, 2012
The ability of legume crops to fix atmospheric nitrogen via a symbiotic association with soil rhizobia makes them an essential component of many agricultural systems. Initiation of this symbiosis requires protein phosphorylation-mediated signaling in response to rhizobial signals named Nod factors. Medicago truncatula (Medicago) is the model system for
Christopher M. Rose, Muthusubramanian eVenkateshwaran, Paul A. Grimsrud, Michael S. Westphall, Michael R. Sussman, Joshua J. Coon, Joshua J. Coon, Jean-Michel eAné   +7 more
openaire   +3 more sources

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Phosphoproteomics analysis of serum from dogs affected with pulmonary hypertension secondary to degenerative mitral valve disease [PDF]

PeerJ
Pulmonary hypertension (PH), a common complication in dogs affected by degenerative mitral valve disease (DMVD), is a progressive disorder characterized by increased pulmonary arterial pressure (PAP) and pulmonary vascular remodeling.
Siriwan Sakarin, Anudep Rungsipipat, Sittiruk Roytrakul, Janthima Jaresitthikunchai, Narumon Phaonakrop, Sawanya Charoenlappanit, Siriwan Thaisakun, Sirilak Surachetpong   +7 more
doaj   +2 more sources

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source