Results 41 to 50 of about 46,894 (190)

Proteomic analysis of phosphoproteins sensitive to a phosphatidylinositol 3-kinase inhibitor, ZSTK474, by using SELDI-TOF MS [PDF]

, 2009
Background Phosphoproteins play important roles in a vast series of biological processes. Recent proteomic technologies offer the comprehensive analyses of phosphoproteins.
Yamori Takao, Akashi Tetsuyuki
core   +2 more sources

Proteomic analysis discovers the differential expression of novel proteins and phosphoproteins in meningioma including NEK9, HK2 and SET and deregulation of RNA metabolismResearch in context

EBioMedicine, 2019
Background: Meningioma is the most frequent primary intracranial tumour. Surgical resection remains the main therapeutic option as pharmacological intervention is hampered by poor knowledge of their proteomic signature.
Jemma Dunn, Sara Ferluga, Vikram Sharma, Matthias Futschik, David A. Hilton, Claire L. Adams, Edwin Lasonder, C. Oliver Hanemann   +7 more
doaj   +1 more source

Site-specific incorporation of phosphotyrosine using an expanded genetic code. [PDF]

, 2017
Access to phosphoproteins with stoichiometric and site-specific phosphorylation status is key to understanding the role of protein phosphorylation.
Allison Wong, Bing Yang, C Fan, C Hoppmann, Christian Hoppmann, CS Tan, DB Johnson, DT Rogerson, H-G Chao, HS Park, J Xie, JJ Ottesen, JK Takimoto, JP Oza, Kevan M Shokat, L Wang, Lei Wang, M Jbara, MK Tarrant, NL Pirman, P Blume-Jensen, PV Hornbeck, R Serwa, R Yau, RA Chong, S George, SG Julien, Shuwei Li, SJ Humphrey, SW Santoro, T Hunter, T Wauer, Tony Hunter, VK Lacey, WA Lim, Z Chen, Z Xiang   +36 more
core   +1 more source

Integrative features of the yeast phosphoproteome and protein-protein interaction map. [PDF]

PLoS Computational Biology, 2011
Following recent advances in high-throughput mass spectrometry (MS)-based proteomics, the numbers of identified phosphoproteins and their phosphosites have greatly increased in a wide variety of organisms.
Nozomu Yachie, Rintaro Saito, Naoyuki Sugiyama, Masaru Tomita, Yasushi Ishihama   +4 more
doaj   +1 more source

Gingival Enlargement Associated with Orthodontics Appliance Increases Protein Carbonylation and Alters Phosphorylation of Salivary Proteome

Dentistry Journal
Gingival enlargement is a common clinical sign in the gingival diseases associated with orthodontic treatment. Its biological mechanisms are not completely understood; nevertheless, the biochemical changes associated with these inflammatory and ...
Zulieth Lopez Arrieta, Erika Rodríguez-Cavallo, Darío Méndez-Cuadro   +2 more
doaj   +1 more source

Human Parainfluenza Virus 3 Phosphoprotein Is a Tetramer and Shares Structural and Interaction Features with Ebola Phosphoprotein VP35

Biomolecules, 2021
The human parainfluenza virus 3 (HPIV3) poses a risk for pneumonia development in young children and immunocompromised patients. To investigate mechanisms of HPIV3 pathogenesis, we characterized the association state and host protein interactions of ...
Joaquin Rodriguez Galvan, Brianna Donner, Cat Hoang Veseley, Patrick Reardon, Heather M. Forsythe, Jesse Howe, Gretchen Fujimura, Elisar Barbar   +7 more
doaj   +1 more source

The cell surface receptor Tartan is a potential in vivo substrate for the receptor tyrosine phosphatase Ptp52F [PDF]

, 2009
Receptor-linked protein-tyrosine phosphatases (RPTPs) are essential regulators of axon guidance and synaptogenesis in Drosophila, but the signaling pathways in which they function are poorly defined.
Bugga, Lakshmi, Ratnaparkhi, Anuradha, Zinn, Kai   +2 more
core   +2 more sources

Quantitative and functional post-translational modification proteomics reveals that TREPH1 plays a role in plant thigmomorphogenesis

, 2018
Plants can sense both intracellular and extracellular mechanical forces and can respond through morphological changes. The signaling components responsible for mechanotransduction of the touch response are largely unknown.
Braam, Janet, Chehab, E. Wassim, Dai, Chen, Li, Ning, Liu, Jun, Liu, Shichang, Qing, Dongjin, Ren, Feng, Wang, Kai, Wu, Madeline, Yang, Zhu, Zhang, Weiping, Zheng, Qingsong   +12 more
core   +2 more sources

Phosphoproteins associated with cyclic nucleotide stimulation of ciliary motility in Paramecium [PDF]

, 1990
Permeabilized, MgATP-reactivated cells of Paramecium (models) respond to cyclic AMP and cyclic GMP by increasing forward swimming speed. In association with the motile response, cyclic AMP and 8-bromo-cyclic GMP (8-Br-cyclic GMP) stimulated protein ...
Bonini, Nancy M., Nelson, David L.
core  

Extensive differential protein phosphorylation as intraerythrocytic Plasmodium falciparumschizonts develop into extracellular invasive merozoites [PDF]

, 2015
Pathology of the most lethal form of malaria is caused by Plasmodium falciparum asexual blood stages and initiated by merozoite invasion of erythrocytes.
Grainger, Munira, Green, Judith L., Holder, Anthony A., Langsley, Gordon, Lasonder, Edwin   +4 more
core   +1 more source