Results 61 to 70 of about 46,894 (190)

Calsequestrins in skeletal and cardiac muscle from adult Danio rerio [PDF]

open access: yes, 2015
Calsequestrin (Casq) is a high capacity, low affinity Ca2+-binding protein, critical for Ca2+-buffering in cardiac and skeletal muscle sarcoplasmic reticulum. All vertebrates have multiple genes encoding for different Casq isoforms.
Argenton, Francesco   +6 more
core   +1 more source

Budded Autographa californica NPV 64K protein: Further biochemical analysis and effects of postimmunoprecipitation sample preparation conditions. [PDF]

open access: yes, 1984
Previously it was shown that AcV1, a neutralizing monoclonal antibody of the Autographa californica nuclear polyhedrosis virus-budded phenotype reacted with a surface antigen present on infected cells during virus budding, and in the viral envelope (L. E.
Goldsmith, PA, Volkman, LE
core  

Cytokine-associated drug toxicity in human hepatocytes is associated signaling network dysregulation [PDF]

open access: yes, 2009
Refer to Web version on PubMed Central for supplementary material.Idiosyncratic drug hepatotoxicity is a major problem in pharmaceutical development due to poor prediction capability of standard preclinical toxicity assessments and limited knowledge of ...
Ballif   +50 more
core   +1 more source

One-step preservation of phosphoproteins and tissue morphology at room temperature for diagnostic and research specimens. [PDF]

open access: yesPLoS ONE, 2011
There is an urgent need to measure phosphorylated cell signaling proteins in cancer tissue for the individualization of molecular targeted kinase inhibitor therapy. However, phosphoproteins fluctuate rapidly following tissue procurement.
Claudius Mueller   +11 more
doaj   +1 more source

Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer [PDF]

open access: yes, 2014
Our understanding of breast cancer heterogeneity at the protein level is limited despite proteins being the ultimate effectors of cellular functions. We investigated the heterogeneity of breast cancer (41 primary tumors and 15 breast cancer cell lines ...
Al-Ejeh, Fares   +12 more
core   +1 more source

Activation of Ciona sperm motility: phosphorylation of dynein polypeptides and effects of a tyrosine kinase inhibitor [PDF]

open access: yes, 1991
A high molecular mass dynein ATPase polypeptide and a 18–20 kDa dynein light chain of Ciona sperm flagella are phosphorylated during in vivo activation of motility or in vitro activation of motility by incubation with cyclic AMP.
Brokaw, Charles J., Dey, Chinmoy S.
core  

Peanut stunt virus and its satellite RNA trigger changes in phosphorylation in N-benthamiana infected plants at the early stage of the infection [PDF]

open access: yes, 2018
Signaling in host plants is an integral part of a successful infection by pathogenic RNA viruses. Therefore, identifying early signaling events in host plants that play an important role in establishing the infection process will help our understanding ...
De Smet, Ive   +4 more
core   +2 more sources

PAPE (Prefractionation-Assisted Phosphoprotein Enrichment): A Novel Approach for Phosphoproteomic Analysis of Green Tissues from Plants

open access: yesProteomes, 2013
Phosphorylation is an important post-translational protein modification with regulatory roles in diverse cellular signaling pathways. Despite recent advances in mass spectrometry, the detection of phosphoproteins involved in signaling is still ...
Ines Lassowskat   +3 more
doaj   +1 more source

TiO2 NPs@UiO-66 TiZr dual active centers demonstrate excellent performance in phosphoprotein detection in sweat

open access: yesSensing and Bio-Sensing Research
Protein phosphorylation in sweat metabolites plays a key role in nerve activity, muscle contraction, and other activities, and abnormal protein phosphorylation may lead to diseases such as neurodegenerative disorders. Real-time non-invasive monitoring of
Ce Bian   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy