Results 11 to 20 of about 12,382 (182)
Phosphoproteome Discovery in Human Biological Fluids
Proteomes, 2016 Phosphorylation plays a critical role in regulating protein function and thus influences a vast spectrum of cellular processes. With the advent of modern bioanalytical technologies, examination of protein phosphorylation on a global scale has become one ...
Francesco Giorgianni
exaly +4 more sources
Frontiers in Plant Science, 2023 The 2, 4-epibrassinolide (EBR) significantly increased plants cold tolerance. However, mechanisms of EBR in regulating cold tolerance in phosphoproteome and proteome levels have not been reported. The mechanism of EBR regulating cold response in cucumber
Xianchang Yu, Qinghua Di, Mengdi Zhou
exaly +3 more sources
Frontiers in Plant ScienceTobacco (Nicotiana tabacum L.) is an important industrial crop, which is sensitive to chilling stress. Tobacco seedlings that have been subjected to chilling stress readily flower early, which seriously affects the yield and quality of their leaves ...
Tingyu Xu, Zhenchen Zhang, Xiaoying Pan
exaly +3 more sources
Cells, 2021 To investigate the biological role of protein phosphorylation in human nonfunctional pituitary neuroendocrine tumors (NF-PitNETs), proteins extracted from NF-PitNET and control tissues were analyzed with tandem mass tag (TMT)-based quantitative ...
Jiajia Li +4 more
doaj +1 more source
BMC Plant Biology, 2021 Background Proteins are the workforce of the cell and their phosphorylation status tailors specific responses efficiently. One of the main challenges of phosphoproteomic approaches is to deconvolute biological processes that specifically respond to an ...
Denise S. Arico +3 more
doaj +1 more source
Phosphoproteome Dynamics of Streptomyces rimosus during Submerged Growth and Antibiotic Production
mSystems, 2022 Streptomyces rimosus is an industrial streptomycete, best known as a producer of oxytetracycline, one of the most widely used antibiotics. Despite the significant contribution of Streptomyces species to the pharmaceutical industry, most omics analyses ...
Ela Šarić +10 more
doaj +1 more source
Animals, 2022 Improvements in the feeding of calves are of increasing importance for the development of the dairy industry. While colostrum is essential for the health of newborn calves, knowledge of protein phosphorylation alterations in neonatal calves that are fed ...
Xiaowei Zhao +3 more
doaj +1 more source
Proteogenomic characterization of cholangiocarcinoma
Hepatology, EarlyView., 2022 Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng +18 more
wiley +1 more source
Systems-level phosphoproteomics reveals calcium/calmodulin-dependent protein kinase kinase 2-driven kinase signaling underlying malignant phenotypes in gastric cancer. [PDF]
J Cell Commun SignalCAMKK2 inhibition induces extensive phosphoproteomic remodeling associated with cell cycle regulation, RNA processing, and kinase signaling networks in gastric cancer. Integrated systems‐level analyses identified dysregulated CDK, SRPK, MAPK, and AKT signaling pathways underlying malignant phenotypes and highlighted CAMKK2 as a potential therapeutic ...
Najar MA, Prasad TSK, Modi PK.
europepmc +2 more sources
Biology, 2020 Diatoms are major contributors to global primary production and their populations in the modern oceans are affected by availability of iron, nitrogen, phosphate, silica, and other trace metals, vitamins, and infochemicals.
Maxine H. Tan +6 more
doaj +1 more source