Results 121 to 130 of about 20,110 (245)

Evolutionary patterns of phosphorylated serines [PDF]

, 2011
Posttranslationally modified amino acids are chemically distinct types of amino acids and in terms of evolution they might behave differently from their non-modified counterparts.
Yerbol Z Kurmangaliyev, Alexander Goland, Mikhail S Gelfand   +2 more
core   +2 more sources

A Hanks‐type bacterial kinase, PknS, directly phosphorylates the alternative sigma factor EcfK to promote resistance to protist predation

The FEBS Journal, EarlyView.
The Xanthomonas citri Hanks‐type kinase PknS autophosphorylates and directly phosphorylates the alternative sigma factor EcfK at five residues. Besides the conserved residue T51 in the σ2 domain, phosphorylation of a residue in the linker between σ2 and σ4 is critical for EcfK activation by promoting its interaction with a positively charged pocket in ...
Lídia dos Passos Lima, Dev Sriranganadane, Daiane Laise da Silva, Natália C. Drebes Dörr, Enzo Breviglieri Sichi Mello, Caio Vinicius dos Reis, Rogério Ferreira Lourenço, José Felipe Teixeira da Silva Santos, Anita Salmazo, Brenno Wendler Miranda, Katlin B. Massirer, Rafael M. Couñago, Cristina E. Alvarez‐Martinez   +12 more
wiley   +1 more source

Toward a Systems-Level View of Dynamic Phosphorylation Networks

Frontiers in Genetics, 2014
To better understand how cells sense and respond to their environment, it is important to understand the organization and regulation of the phosphorylation networks that underlie most cellular signal transduction pathways.
Robert Howard Newman, Jin eZhang, Jin eZhang, Jin eZhang, Jin eZhang, Heng eZhu, Heng eZhu   +6 more
doaj   +1 more source

Role of Protein Phosphorylation in the Regulation of Cell Cycle and DNA-Related Processes in Bacteria [PDF]

, 2016
In all living organisms, the phosphorylation of proteins modulates various aspects of their functionalities. In eukaryotes, protein phosphorylation plays a key role in cell signaling, gene expression, and differentiation.
Derouiche, Abderahmane, Garcia-Garcia, Transito, Mijakovic, Ivan, Noirot-Gros, Marie-Francoise, Poncet, Sandrine, Shi, Lei   +5 more
core   +4 more sources

Hybrid sorghum breeding in China: A historical review and perspectives

Journal of Integrative Plant Biology, EarlyView.
To commemorate the 60th anniversary of the promotion and application of three‐line hybrid sorghum in China, this review highlights pivotal scientific breakthroughs, systematically summarizes the progress in hybrid sorghum breeding and dwarf sorghum breeding in the country, and presents an outlook on the future of sorghum breeding.
Xiangxiang Meng, Lu Li, Qian Qian, Liang Jiang, Zhaosheng Kong   +4 more
wiley   +1 more source

Designing experiments to discriminate families of logic models

Frontiers in Bioengineering and Biotechnology, 2015
Logic models of signaling pathways are a promising way of building effective in silico functional models of a cell, in particular of signaling pathways.
Santiago eVidela, Santiago eVidela, Santiago eVidela, Santiago eVidela, Irina eKonokotina, Leonidas eAlexopoulos, Julio eSaez-Rodriguez, Torsten eSchaub, Anne eSiegel, Anne eSiegel, Carito eGuziolowski   +10 more
doaj   +1 more source

Full‐Spectrum Medicinal Cannabis Plant Extract 0.08% THC (NTI164) Improves Symptoms of Rett Syndrome: An Open‐Label Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim The aim of this Phase I/II open‐label study was to assess the safety and efficacy of NTI164, a novel full‐spectrum medicinal cannabis plant extract 0.08% Δ‐9‐tetrahydrocannabinol (THC), in Rett syndrome (RTT). Methods Eleven female participants (5–16 years) with a pathogenic variant in the MECP2 gene were recruited to this study, receiving
B. A. Keating, Y. Ogru, T. G. Duthy, L. Douglas, K. Lichkus, E. Isikgel, M. C. Fahey, C. Ellaway   +7 more
wiley   +1 more source

Subclass III SnRK2 Kinases Coordinate Starch and Storage Protein Synthesis During Maize Kernel Development

Plant Biotechnology Journal, EarlyView.
ABSTRACT Enhancing both starch and protein accumulation is a key strategy for improving maize yield and quality. Achieving this goal requires an in‐depth understanding of the regulatory mechanisms that integrate these pathways. Here, we demonstrate that functionally redundant subclass III SNF1‐related protein kinase 2s (SnRK2s) act as central ...
Yayun Wang, Tiandan Long, Changqing Mao, Shan Feng, Qiang Liao, Yufeng Hu, Junjie Zhang, Hanmei Liu, Yinghong Liu, Xiujun Fan, Lei Gao, Canmei Cun, Binjie Xu, Daqiu Zhao, Jing Wang, Yubi Huang, Yangping Li   +16 more
wiley   +1 more source

FvMAPK6‐Mediated FvMYB44s/FvSWEET1 Dual‐Layer Regulation Modulates Sugar Accumulation in Strawberry Fruit, With FvSPS3 Enabling Quality–Yield Balance

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sugar content is a key determinant of fruit quality, and sugars also act as signalling molecules that regulate ripening processes, including anthocyanin accumulation. However, the molecular mechanisms underlying sugar accumulation and sugar signal‐mediated ripening remain incompletely understood.
Qianqian Feng, Lingzhi Wei, Ting Liu, Kexin Wang, Xiaojing Li, Chuang Liu, Ronghui Sun, Xia Li, Zhaonan Yin, Yanrong Wei, Huazhao Yuan, Qian Li, Bingbing Li   +12 more
wiley   +1 more source

Fully Tunable Phosphorylation of RPS6A Ensures the Successful Development of Arabidopsis Seedlings

Plant, Cell &Environment, EarlyView.
ABSTRACT Light enhances protein translation, enabling young seedlings to rapidly and timely acquire photosynthetic capacities. Sequential phosphorylation of ribosomal protein S6 (RPS6) was implicated in the light‐enhanced translation; however, the exact phosphorylation sites and the biological relevance of RPS6 multi‐phosphorylation in seedling ...
Yueh Cho, Guan‐Hong Chen, Shu‐Hsing Wu   +2 more
wiley   +1 more source